5KH2 | Genus

Total Genus 84

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	84
sequence length	229
structure length	224
Chain Sequence	QVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNRRH

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 224 atoms

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224 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase. pubmed doi rcsb
molecule keywords	Isoprenyl transferase
molecule tags	Transferase
source organism	Streptococcus pneumoniae serotype 4 (strain atcc baa-334 / tigr4)
total genus	84
structure length	224
sequence length	229
chains with identical sequence	B, C, D
ec nomenclature	ec 2.5.1.-:
pdb deposition date	2016-06-14

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01255	Prenyltransf	Putative undecaprenyl diphosphate synthase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1180.10	Alpha Beta	3-Layer(aba) Sandwich	Undecaprenyl pyrophosphate synthetase	Decaprenyl diphosphate synthase-like	5kh2A00

5HXOA 1UEHA 4U82A 3QASA 5KH2A 1X09A 1X07A 2VG4A 4H38A 3SGXA 2E9CA 3WQKA 2E9DA 5HXNA 3SGVA 2VFWA 3WYJA 2VG3A 3WYIA 5HXTA 2DTNA 4H3AA 4ONCA 5HC6A 1X06A 4H8EA 3SH0A 5HXQA 2D2RA 1X08A 5HXPA 4H2OA 4CMXA 5KH4A 5CQJA 3WQMA 4CMWA 1JP3A 2E98A 2VG1A 2VG2A 4Q9MA 4H3CA 3UGSA 3WQNA 2E99A 4H2MA 3WQLA 4CMVA 5KH5A 4KT8A 1F75A 4Q9OA 3SGTA 2E9AA 4H2JA 3TH8A 2VG0A 5HC8A 1V7UA 5HC7A 5CQBA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5HXO A;  1UEH A;  4U82 A;  3QAS A;  5KH2 A;  1X09 A;  1X07 A;  2VG4 A;  4H38 A;  3SGX A;  2E9C A;  3WQK A;  2E9D A;  5HXN A;  3SGV A;  2VFW A;  3WYJ A;  2VG3 A;  3WYI A;  5HXT A;  2DTN A;  4H3A A;  4ONC A;  5HC6 A;  1X06 A;  4H8E A;  3SH0 A;  5HXQ A;  2D2R A;  1X08 A;  5HXP A;  4H2O A;  4CMX A;  5KH4 A;  5CQJ A;  3WQM A;  4CMW A;  1JP3 A;  2E98 A;  2VG1 A;  2VG2 A;  4Q9M A;  4H3C A;  3UGS A;  3WQN A;  2E99 A;  4H2M A;  3WQL A;  4CMV A;  5KH5 A;  4KT8 A;  1F75 A;  4Q9O A;  3SGT A;  2E9A A;  4H2J A;  3TH8 A;  2VG0 A;  5HC8 A;  1V7U A;  5HC7 A;  5CQB A; 
#chains in the Genus database with same CATH topology
 5HXO A;  1UEH A;  4U82 A;  3QAS A;  5KH2 A;  1X09 A;  1X07 A;  2VG4 A;  4H38 A;  3SGX A;  2E9C A;  3WQK A;  2E9D A;  5HXN A;  3SGV A;  2VFW A;  3WYJ A;  2VG3 A;  3WYI A;  5HXT A;  2DTN A;  4H3A A;  4ONC A;  5HC6 A;  1X06 A;  4H8E A;  3SH0 A;  5HXQ A;  2D2R A;  1X08 A;  5HXP A;  4H2O A;  4CMX A;  5KH4 A;  5CQJ A;  3WQM A;  4CMW A;  1JP3 A;  2E98 A;  2VG1 A;  2VG2 A;  4Q9M A;  4H3C A;  3UGS A;  3WQN A;  2E99 A;  4H2M A;  3WQL A;  4CMV A;  5KH5 A;  4KT8 A;  1F75 A;  4Q9O A;  3SGT A;  2E9A A;  4H2J A;  3TH8 A;  2VG0 A;  5HC8 A;  1V7U A;  5HC7 A;  5CQB A; 
#chains in the Genus database with same CATH homology
 5HXO A;  1UEH A;  4U82 A;  3QAS A;  5KH2 A;  1X09 A;  1X07 A;  2VG4 A;  4H38 A;  3SGX A;  2E9C A;  3WQK A;  2E9D A;  5HXN A;  3SGV A;  2VFW A;  3WYJ A;  2VG3 A;  3WYI A;  5HXT A;  2DTN A;  4H3A A;  4ONC A;  5HC6 A;  1X06 A;  4H8E A;  3SH0 A;  5HXQ A;  2D2R A;  1X08 A;  5HXP A;  4H2O A;  4CMX A;  5KH4 A;  5CQJ A;  3WQM A;  4CMW A;  1JP3 A;  2E98 A;  2VG1 A;  2VG2 A;  4Q9M A;  4H3C A;  3UGS A;  3WQN A;  2E99 A;  4H2M A;  3WQL A;  4CMV A;  5KH5 A;  4KT8 A;  1F75 A;  4Q9O A;  3SGT A;  2E9A A;  4H2J A;  3TH8 A;  2VG0 A;  5HC8 A;  1V7U A;  5HC7 A;  5CQB A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5KH2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations