5KH4 | Genus

Total Genus 82

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	82
sequence length	231
structure length	231
Chain Sequence	EVPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase. pubmed doi rcsb
molecule keywords	Isoprenyl transferase
molecule tags	Transferase
source organism	Streptococcus pneumoniae serotype 4 (strain atcc baa-334 / tigr4)
total genus	82
structure length	231
sequence length	231
chains with identical sequence	B
ec nomenclature	ec 2.5.1.-:
pdb deposition date	2016-06-14

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01255	Prenyltransf	Putative undecaprenyl diphosphate synthase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1180.10	Alpha Beta	3-Layer(aba) Sandwich	Undecaprenyl pyrophosphate synthetase	Decaprenyl diphosphate synthase-like	5kh4A00

3WQKA 5KH4A 2E9CA 4H3CA 2VG3A 1X07A 3UGSA 5KH2A 1X09A 2D2RA 4KT8A 2E9AA 4H2JA 5HXPA 3SH0A 5HXQA 1UEHA 5HXNA 3WYIA 4ONCA 1JP3A 3TH8A 5HXTA 1F75A 2E98A 4H3AA 1V7UA 5HC8A 2VFWA 2VG4A 5HC7A 3WYJA 1X08A 2VG2A 2E9DA 5HC6A 4CMXA 2E99A 1X06A 4H2MA 2DTNA 2VG0A 3SGVA 3WQLA 3WQNA 4CMWA 2VG1A 4Q9MA 3QASA 4H2OA 4H38A 3SGTA 3SGXA 4CMVA 5KH5A 3WQMA 5CQBA 4H8EA 4Q9OA 5HXOA 4U82A 5CQJA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3WQK A;  5KH4 A;  2E9C A;  4H3C A;  2VG3 A;  1X07 A;  3UGS A;  5KH2 A;  1X09 A;  2D2R A;  4KT8 A;  2E9A A;  4H2J A;  5HXP A;  3SH0 A;  5HXQ A;  1UEH A;  5HXN A;  3WYI A;  4ONC A;  1JP3 A;  3TH8 A;  5HXT A;  1F75 A;  2E98 A;  4H3A A;  1V7U A;  5HC8 A;  2VFW A;  2VG4 A;  5HC7 A;  3WYJ A;  1X08 A;  2VG2 A;  2E9D A;  5HC6 A;  4CMX A;  2E99 A;  1X06 A;  4H2M A;  2DTN A;  2VG0 A;  3SGV A;  3WQL A;  3WQN A;  4CMW A;  2VG1 A;  4Q9M A;  3QAS A;  4H2O A;  4H38 A;  3SGT A;  3SGX A;  4CMV A;  5KH5 A;  3WQM A;  5CQB A;  4H8E A;  4Q9O A;  5HXO A;  4U82 A;  5CQJ A; 
#chains in the Genus database with same CATH topology
 3WQK A;  5KH4 A;  2E9C A;  4H3C A;  2VG3 A;  1X07 A;  3UGS A;  5KH2 A;  1X09 A;  2D2R A;  4KT8 A;  2E9A A;  4H2J A;  5HXP A;  3SH0 A;  5HXQ A;  1UEH A;  5HXN A;  3WYI A;  4ONC A;  1JP3 A;  3TH8 A;  5HXT A;  1F75 A;  2E98 A;  4H3A A;  1V7U A;  5HC8 A;  2VFW A;  2VG4 A;  5HC7 A;  3WYJ A;  1X08 A;  2VG2 A;  2E9D A;  5HC6 A;  4CMX A;  2E99 A;  1X06 A;  4H2M A;  2DTN A;  2VG0 A;  3SGV A;  3WQL A;  3WQN A;  4CMW A;  2VG1 A;  4Q9M A;  3QAS A;  4H2O A;  4H38 A;  3SGT A;  3SGX A;  4CMV A;  5KH5 A;  3WQM A;  5CQB A;  4H8E A;  4Q9O A;  5HXO A;  4U82 A;  5CQJ A; 
#chains in the Genus database with same CATH homology
 3WQK A;  5KH4 A;  2E9C A;  4H3C A;  2VG3 A;  1X07 A;  3UGS A;  5KH2 A;  1X09 A;  2D2R A;  4KT8 A;  2E9A A;  4H2J A;  5HXP A;  3SH0 A;  5HXQ A;  1UEH A;  5HXN A;  3WYI A;  4ONC A;  1JP3 A;  3TH8 A;  5HXT A;  1F75 A;  2E98 A;  4H3A A;  1V7U A;  5HC8 A;  2VFW A;  2VG4 A;  5HC7 A;  3WYJ A;  1X08 A;  2VG2 A;  2E9D A;  5HC6 A;  4CMX A;  2E99 A;  1X06 A;  4H2M A;  2DTN A;  2VG0 A;  3SGV A;  3WQL A;  3WQN A;  4CMW A;  2VG1 A;  4Q9M A;  3QAS A;  4H2O A;  4H38 A;  3SGT A;  3SGX A;  4CMV A;  5KH5 A;  3WQM A;  5CQB A;  4H8E A;  4Q9O A;  5HXO A;  4U82 A;  5CQJ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5KH4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations