5KH4 | Genus

Total Genus 82

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	82
sequence length	231
structure length	231
Chain Sequence	EVPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase. pubmed doi rcsb
molecule keywords	Isoprenyl transferase
molecule tags	Transferase
source organism	Streptococcus pneumoniae serotype 4 (strain atcc baa-334 / tigr4)
total genus	82
structure length	231
sequence length	231
chains with identical sequence	B
ec nomenclature	ec 2.5.1.-:
pdb deposition date	2016-06-14

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01255	Prenyltransf	Putative undecaprenyl diphosphate synthase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1180.10	Alpha Beta	3-Layer(aba) Sandwich	Undecaprenyl pyrophosphate synthetase	Decaprenyl diphosphate synthase-like	5kh4A00

5CQJA 5KH4A 2E99A 3WQMA 4H2JA 2VG2A 3UGSA 5HC7A 2D2RA 3SGVA 3WQLA 4CMVA 1X09A 2E9CA 3QASA 5HXQA 2E9AA 5HC8A 2VG0A 4Q9MA 3WQKA 2DTNA 4KT8A 2E9DA 2VFWA 5HXTA 5KH2A 4H38A 5CQBA 1X06A 3TH8A 5HXNA 1X08A 4Q9OA 5HXPA 4H3CA 4CMWA 1JP3A 2VG1A 4H2OA 3SH0A 4U82A 3WYIA 3SGXA 1V7UA 3SGTA 5HXOA 1UEHA 4H2MA 4H8EA 1F75A 4ONCA 3WQNA 1X07A 4CMXA 2VG3A 5KH5A 2E98A 4H3AA 2VG4A 3WYJA 5HC6A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5CQJ A;  5KH4 A;  2E99 A;  3WQM A;  4H2J A;  2VG2 A;  3UGS A;  5HC7 A;  2D2R A;  3SGV A;  3WQL A;  4CMV A;  1X09 A;  2E9C A;  3QAS A;  5HXQ A;  2E9A A;  5HC8 A;  2VG0 A;  4Q9M A;  3WQK A;  2DTN A;  4KT8 A;  2E9D A;  2VFW A;  5HXT A;  5KH2 A;  4H38 A;  5CQB A;  1X06 A;  3TH8 A;  5HXN A;  1X08 A;  4Q9O A;  5HXP A;  4H3C A;  4CMW A;  1JP3 A;  2VG1 A;  4H2O A;  3SH0 A;  4U82 A;  3WYI A;  3SGX A;  1V7U A;  3SGT A;  5HXO A;  1UEH A;  4H2M A;  4H8E A;  1F75 A;  4ONC A;  3WQN A;  1X07 A;  4CMX A;  2VG3 A;  5KH5 A;  2E98 A;  4H3A A;  2VG4 A;  3WYJ A;  5HC6 A; 
#chains in the Genus database with same CATH topology
 5CQJ A;  5KH4 A;  2E99 A;  3WQM A;  4H2J A;  2VG2 A;  3UGS A;  5HC7 A;  2D2R A;  3SGV A;  3WQL A;  4CMV A;  1X09 A;  2E9C A;  3QAS A;  5HXQ A;  2E9A A;  5HC8 A;  2VG0 A;  4Q9M A;  3WQK A;  2DTN A;  4KT8 A;  2E9D A;  2VFW A;  5HXT A;  5KH2 A;  4H38 A;  5CQB A;  1X06 A;  3TH8 A;  5HXN A;  1X08 A;  4Q9O A;  5HXP A;  4H3C A;  4CMW A;  1JP3 A;  2VG1 A;  4H2O A;  3SH0 A;  4U82 A;  3WYI A;  3SGX A;  1V7U A;  3SGT A;  5HXO A;  1UEH A;  4H2M A;  4H8E A;  1F75 A;  4ONC A;  3WQN A;  1X07 A;  4CMX A;  2VG3 A;  5KH5 A;  2E98 A;  4H3A A;  2VG4 A;  3WYJ A;  5HC6 A; 
#chains in the Genus database with same CATH homology
 5CQJ A;  5KH4 A;  2E99 A;  3WQM A;  4H2J A;  2VG2 A;  3UGS A;  5HC7 A;  2D2R A;  3SGV A;  3WQL A;  4CMV A;  1X09 A;  2E9C A;  3QAS A;  5HXQ A;  2E9A A;  5HC8 A;  2VG0 A;  4Q9M A;  3WQK A;  2DTN A;  4KT8 A;  2E9D A;  2VFW A;  5HXT A;  5KH2 A;  4H38 A;  5CQB A;  1X06 A;  3TH8 A;  5HXN A;  1X08 A;  4Q9O A;  5HXP A;  4H3C A;  4CMW A;  1JP3 A;  2VG1 A;  4H2O A;  3SH0 A;  4U82 A;  3WYI A;  3SGX A;  1V7U A;  3SGT A;  5HXO A;  1UEH A;  4H2M A;  4H8E A;  1F75 A;  4ONC A;  3WQN A;  1X07 A;  4CMX A;  2VG3 A;  5KH5 A;  2E98 A;  4H3A A;  2VG4 A;  3WYJ A;  5HC6 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5KH4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations