5KH4 | Genus

Total Genus 82

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	82
sequence length	231
structure length	231
Chain Sequence	EVPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 231 atoms

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231 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase. pubmed doi rcsb
molecule keywords	Isoprenyl transferase
molecule tags	Transferase
source organism	Streptococcus pneumoniae serotype 4 (strain atcc baa-334 / tigr4)
total genus	82
structure length	231
sequence length	231
chains with identical sequence	B
ec nomenclature	ec 2.5.1.-:
pdb deposition date	2016-06-14

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01255	Prenyltransf	Putative undecaprenyl diphosphate synthase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1180.10	Alpha Beta	3-Layer(aba) Sandwich	Undecaprenyl pyrophosphate synthetase	Decaprenyl diphosphate synthase-like	5kh4A00

5HXQA 2VG2A 3SH0A 4H3CA 4H3AA 5HXNA 2E9CA 2E9DA 4H8EA 3WQLA 4CMVA 4H2OA 3WQKA 3WYJA 4CMWA 1JP3A 2D2RA 2DTNA 1V7UA 4H2JA 5CQBA 2E98A 5KH4A 2E9AA 5HXPA 3WQNA 2E99A 4ONCA 5CQJA 4CMXA 1X09A 3QASA 3SGVA 1F75A 1X06A 4H38A 2VG3A 5KH2A 4H2MA 2VG0A 4KT8A 1X07A 5HXTA 4Q9MA 3SGTA 5HC7A 4U82A 3WYIA 2VFWA 5KH5A 5HC8A 3TH8A 3UGSA 3WQMA 2VG4A 3SGXA 1X08A 1UEHA 5HXOA 2VG1A 4Q9OA 5HC6A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5HXQ A;  2VG2 A;  3SH0 A;  4H3C A;  4H3A A;  5HXN A;  2E9C A;  2E9D A;  4H8E A;  3WQL A;  4CMV A;  4H2O A;  3WQK A;  3WYJ A;  4CMW A;  1JP3 A;  2D2R A;  2DTN A;  1V7U A;  4H2J A;  5CQB A;  2E98 A;  5KH4 A;  2E9A A;  5HXP A;  3WQN A;  2E99 A;  4ONC A;  5CQJ A;  4CMX A;  1X09 A;  3QAS A;  3SGV A;  1F75 A;  1X06 A;  4H38 A;  2VG3 A;  5KH2 A;  4H2M A;  2VG0 A;  4KT8 A;  1X07 A;  5HXT A;  4Q9M A;  3SGT A;  5HC7 A;  4U82 A;  3WYI A;  2VFW A;  5KH5 A;  5HC8 A;  3TH8 A;  3UGS A;  3WQM A;  2VG4 A;  3SGX A;  1X08 A;  1UEH A;  5HXO A;  2VG1 A;  4Q9O A;  5HC6 A; 
#chains in the Genus database with same CATH topology
 5HXQ A;  2VG2 A;  3SH0 A;  4H3C A;  4H3A A;  5HXN A;  2E9C A;  2E9D A;  4H8E A;  3WQL A;  4CMV A;  4H2O A;  3WQK A;  3WYJ A;  4CMW A;  1JP3 A;  2D2R A;  2DTN A;  1V7U A;  4H2J A;  5CQB A;  2E98 A;  5KH4 A;  2E9A A;  5HXP A;  3WQN A;  2E99 A;  4ONC A;  5CQJ A;  4CMX A;  1X09 A;  3QAS A;  3SGV A;  1F75 A;  1X06 A;  4H38 A;  2VG3 A;  5KH2 A;  4H2M A;  2VG0 A;  4KT8 A;  1X07 A;  5HXT A;  4Q9M A;  3SGT A;  5HC7 A;  4U82 A;  3WYI A;  2VFW A;  5KH5 A;  5HC8 A;  3TH8 A;  3UGS A;  3WQM A;  2VG4 A;  3SGX A;  1X08 A;  1UEH A;  5HXO A;  2VG1 A;  4Q9O A;  5HC6 A; 
#chains in the Genus database with same CATH homology
 5HXQ A;  2VG2 A;  3SH0 A;  4H3C A;  4H3A A;  5HXN A;  2E9C A;  2E9D A;  4H8E A;  3WQL A;  4CMV A;  4H2O A;  3WQK A;  3WYJ A;  4CMW A;  1JP3 A;  2D2R A;  2DTN A;  1V7U A;  4H2J A;  5CQB A;  2E98 A;  5KH4 A;  2E9A A;  5HXP A;  3WQN A;  2E99 A;  4ONC A;  5CQJ A;  4CMX A;  1X09 A;  3QAS A;  3SGV A;  1F75 A;  1X06 A;  4H38 A;  2VG3 A;  5KH2 A;  4H2M A;  2VG0 A;  4KT8 A;  1X07 A;  5HXT A;  4Q9M A;  3SGT A;  5HC7 A;  4U82 A;  3WYI A;  2VFW A;  5KH5 A;  5HC8 A;  3TH8 A;  3UGS A;  3WQM A;  2VG4 A;  3SGX A;  1X08 A;  1UEH A;  5HXO A;  2VG1 A;  4Q9O A;  5HC6 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5KH4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations