5KH5 | Genus

Total Genus 82

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	82
sequence length	232
structure length	230
Chain Sequence	TQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNRRHRR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 230 atoms

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230 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase. pubmed doi rcsb
molecule keywords	Isoprenyl transferase
molecule tags	Transferase/transferase inhibitor
source organism	Streptococcus pneumoniae serotype 4 (strain atcc baa-334 / tigr4)
total genus	82
structure length	230
sequence length	232
chains with identical sequence	B
ec nomenclature	ec 2.5.1.-:
pdb deposition date	2016-06-14

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01255	Prenyltransf	Putative undecaprenyl diphosphate synthase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1180.10	Alpha Beta	3-Layer(aba) Sandwich	Undecaprenyl pyrophosphate synthetase	Decaprenyl diphosphate synthase-like	5kh5A00

4Q9OA 1UEHA 3QASA 4KT8A 5CQBA 2E9AA 4H3CA 5HXQA 1JP3A 1F75A 2VG4A 2VG0A 1V7UA 4Q9MA 3WQKA 4CMVA 3TH8A 5KH4A 2VG2A 3SGVA 5HC7A 5HC6A 4H8EA 4H2JA 4ONCA 3WQNA 2E9DA 2DTNA 4H3AA 5KH2A 3UGSA 5HXPA 3SGTA 5HXOA 5HXNA 2D2RA 1X09A 2VFWA 5KH5A 2E99A 2E9CA 4H2MA 5CQJA 2E98A 4CMXA 5HC8A 4CMWA 3WYIA 3WYJA 3WQMA 4U82A 5HXTA 1X08A 3SGXA 4H38A 3SH0A 1X07A 2VG1A 1X06A 3WQLA 4H2OA 2VG3A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4Q9O A;  1UEH A;  3QAS A;  4KT8 A;  5CQB A;  2E9A A;  4H3C A;  5HXQ A;  1JP3 A;  1F75 A;  2VG4 A;  2VG0 A;  1V7U A;  4Q9M A;  3WQK A;  4CMV A;  3TH8 A;  5KH4 A;  2VG2 A;  3SGV A;  5HC7 A;  5HC6 A;  4H8E A;  4H2J A;  4ONC A;  3WQN A;  2E9D A;  2DTN A;  4H3A A;  5KH2 A;  3UGS A;  5HXP A;  3SGT A;  5HXO A;  5HXN A;  2D2R A;  1X09 A;  2VFW A;  5KH5 A;  2E99 A;  2E9C A;  4H2M A;  5CQJ A;  2E98 A;  4CMX A;  5HC8 A;  4CMW A;  3WYI A;  3WYJ A;  3WQM A;  4U82 A;  5HXT A;  1X08 A;  3SGX A;  4H38 A;  3SH0 A;  1X07 A;  2VG1 A;  1X06 A;  3WQL A;  4H2O A;  2VG3 A; 
#chains in the Genus database with same CATH topology
 4Q9O A;  1UEH A;  3QAS A;  4KT8 A;  5CQB A;  2E9A A;  4H3C A;  5HXQ A;  1JP3 A;  1F75 A;  2VG4 A;  2VG0 A;  1V7U A;  4Q9M A;  3WQK A;  4CMV A;  3TH8 A;  5KH4 A;  2VG2 A;  3SGV A;  5HC7 A;  5HC6 A;  4H8E A;  4H2J A;  4ONC A;  3WQN A;  2E9D A;  2DTN A;  4H3A A;  5KH2 A;  3UGS A;  5HXP A;  3SGT A;  5HXO A;  5HXN A;  2D2R A;  1X09 A;  2VFW A;  5KH5 A;  2E99 A;  2E9C A;  4H2M A;  5CQJ A;  2E98 A;  4CMX A;  5HC8 A;  4CMW A;  3WYI A;  3WYJ A;  3WQM A;  4U82 A;  5HXT A;  1X08 A;  3SGX A;  4H38 A;  3SH0 A;  1X07 A;  2VG1 A;  1X06 A;  3WQL A;  4H2O A;  2VG3 A; 
#chains in the Genus database with same CATH homology
 4Q9O A;  1UEH A;  3QAS A;  4KT8 A;  5CQB A;  2E9A A;  4H3C A;  5HXQ A;  1JP3 A;  1F75 A;  2VG4 A;  2VG0 A;  1V7U A;  4Q9M A;  3WQK A;  4CMV A;  3TH8 A;  5KH4 A;  2VG2 A;  3SGV A;  5HC7 A;  5HC6 A;  4H8E A;  4H2J A;  4ONC A;  3WQN A;  2E9D A;  2DTN A;  4H3A A;  5KH2 A;  3UGS A;  5HXP A;  3SGT A;  5HXO A;  5HXN A;  2D2R A;  1X09 A;  2VFW A;  5KH5 A;  2E99 A;  2E9C A;  4H2M A;  5CQJ A;  2E98 A;  4CMX A;  5HC8 A;  4CMW A;  3WYI A;  3WYJ A;  3WQM A;  4U82 A;  5HXT A;  1X08 A;  3SGX A;  4H38 A;  3SH0 A;  1X07 A;  2VG1 A;  1X06 A;  3WQL A;  4H2O A;  2VG3 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5KH5A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations