5F4UA

Hiv-1 gp120 complex with bnm-iv-197
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
349
structure length
335
Chain Sequence
KTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKNDMVEQMHEDIISLWDESLKPCVKLTGGSAITQACPKVSFDPIPLHYCAPAGFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNESVNIVCTRPNNIRQAHCNINESKWNNTLQKVGEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYRNGTYNHTGRSSNGTITLQCKIKQIINMWQEVGRAIYAPPIEGEITCNSNITGLLLLRDDTETFRPGGGDMRDNWRSELYKYKVVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C
total genus 78
structure length 335
sequence length 349
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 5f4uA01
4LSUG 1G9MG 4DKUA 5F4RA 3TGRA 5T33G 2NXYA 4JPVG 1GC1G 4OLUG 4YDIG 3TGQA 4JZZA 5TE6G 4H8WG 4LSQG 4LSRG 4OLYG 3SE9G 2QADA 4RFOG 4OLWG 4DKPA 4YFLE 1YYLG 5FECC 5FA2A 2NY3A 4OLZG 4YDKG 2NY4A 1RZJG 1RZKG 4R2GA 4RWYA 4I54A 3RJQA 2NXZA 4J6RG 3SE8G 5F9OG 5F4LA 3U7YG 2I5YG 5IGXG 4I53A 3JWOA 3IDXG 3TIHA 3JWDA 4JM2E 4R4FA 4S1QG 5F4PA 4DVRG 2B4CG 4XNZA 3FUSA 3HI1G 4JKPG 4OLVG 5F9WA 5CD5A 4S1RG 1YYMG 4RFNA 4DKOA 4DVWA 5F96G 4DKQA 4JPWG 4YDLA 3IDYA 4LSSG 4S1SG 5TE4G 4DVXA 3NGBA 4JB9G 4XVTG 3TGTA 5CAYG 2NY6A 4OM0G 4LSTG 4RZ8A 4LAJA 4LSPG 4JDTG 4XVSG 4YDJG 5F4UA 4JZWA 2BF1A 2I60G 2NY1A 4DVVA 4RX4E 4KA2A 1G9NG 4OM1G 4DKRA 2NY0A 2NY2A 5TE7G 4DKVA 4K0AA 4R4NA 2NY7G 4OLXG 2NY5G 3LQAG 4DVTA 5KJRG 4XNYG 4YE4G 5I9QA 4XMPG 3TGSA 4DVSA 4LSVG 4P9HG
chains in the Genus database with same CATH superfamily
4LSUG 1G9MG 4DKUA 5F4RA 3TGRA 5T33G 2NXYA 4JPVG 1GC1G 4OLUG 4YDIG 3TGQA 4JZZA 5TE6G 4H8WG 4LSQG 4LSRG 4OLYG 3SE9G 2QADA 4RFOG 4OLWG 4DKPA 4YFLE 1YYLG 5FECC 5FA2A 2NY3A 4OLZG 4YDKG 2NY4A 1RZJG 1RZKG 4R2GA 4RWYA 4I54A 3RJQA 2NXZA 4J6RG 3SE8G 5F9OG 5F4LA 3U7YG 2I5YG 5IGXG 4I53A 3JWOA 3IDXG 3TIHA 3JWDA 4JM2E 4R4FA 4S1QG 5F4PA 4DVRG 2B4CG 4XNZA 3FUSA 3HI1G 4JKPG 4OLVG 5F9WA 5CD5A 4S1RG 1YYMG 4RFNA 4DKOA 4DVWA 5F96G 4DKQA 4JPWG 4YDLA 3IDYA 4LSSG 4S1SG 5TE4G 4DVXA 3NGBA 4JB9G 4XVTG 3TGTA 5CAYG 2NY6A 4OM0G 4LSTG 4RZ8A 4LAJA 4LSPG 4JDTG 4XVSG 4YDJG 5F4UA 4JZWA 2BF1A 2I60G 2NY1A 4DVVA 4RX4E 4KA2A 1G9NG 4OM1G 4DKRA 2NY0A 2NY2A 5TE7G 4DKVA 4K0AA 4R4NA 2NY7G 4OLXG 2NY5G 3LQAG 4DVTA 5KJRG 4XNYG 4YE4G 5I9QA 4XMPG 3TGSA 4DVSA 4LSVG 4P9HG
chains in the Genus database with same CATH topology
4LSUG 1G9MG 4DKUA 5F4RA 3TGRA 5T33G 2NXYA 4JPVG 1GC1G 4OLUG 4YDIG 3TGQA 4JZZA 5TE6G 4H8WG 4LSQG 4LSRG 4OLYG 3SE9G 2QADA 4RFOG 4OLWG 4DKPA 4YFLE 1YYLG 5FECC 5FA2A 2NY3A 4OLZG 4YDKG 2NY4A 1RZJG 1RZKG 4R2GA 4RWYA 4I54A 3RJQA 2NXZA 4J6RG 3SE8G 5F9OG 5F4LA 3U7YG 2I5YG 5IGXG 4I53A 3JWOA 3IDXG 3TIHA 3JWDA 4JM2E 4R4FA 4S1QG 5F4PA 4DVRG 2B4CG 4XNZA 3FUSA 3HI1G 4JKPG 4OLVG 5F9WA 5CD5A 4S1RG 1YYMG 4RFNA 4DKOA 4DVWA 5F96G 4DKQA 4JPWG 4YDLA 3IDYA 4LSSG 4S1SG 5TE4G 4DVXA 3NGBA 4JB9G 4XVTG 3TGTA 5CAYG 2NY6A 4OM0G 4LSTG 4RZ8A 4LAJA 4LSPG 4JDTG 4XVSG 4YDJG 5F4UA 4JZWA 2BF1A 2I60G 2NY1A 4DVVA 4RX4E 4KA2A 1G9NG 4OM1G 4DKRA 2NY0A 2NY2A 5TE7G 4DKVA 4K0AA 4R4NA 2NY7G 4OLXG 2NY5G 3LQAG 4DVTA 5KJRG 4XNYG 4YE4G 5I9QA 4XMPG 3TGSA 4DVSA 4LSVG 4P9HG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LSU G;  1G9M G;  4DKU A;  5F4R A;  3TGR A;  5T33 G;  2NXY A;  4JPV G;  1GC1 G;  4OLU G;  4YDI G;  3TGQ A;  4JZZ A;  5TE6 G;  4H8W G;  4LSQ G;  4LSR G;  4OLY G;  3SE9 G;  2QAD A;  4RFO G;  4OLW G;  4DKP A;  4YFL E;  1YYL G;  5FEC C;  5FA2 A;  2NY3 A;  4OLZ G;  4YDK G;  2NY4 A;  1RZJ G;  1RZK G;  4R2G A;  4RWY A;  4I54 A;  3RJQ A;  2NXZ A;  4J6R G;  3SE8 G;  5F9O G;  5F4L A;  3U7Y G;  2I5Y G;  5IGX G;  4I53 A;  3JWO A;  3IDX G;  3TIH A;  3JWD A;  4JM2 E;  4R4F A;  4S1Q G;  5F4P A;  4DVR G;  2B4C G;  4XNZ A;  3FUS A;  3HI1 G;  4JKP G;  4OLV G;  5F9W A;  5CD5 A;  4S1R G;  1YYM G;  4RFN A;  4DKO A;  4DVW A;  5F96 G;  4DKQ A;  4JPW G;  4YDL A;  3IDY A;  4LSS G;  4S1S G;  5TE4 G;  4DVX A;  3NGB A;  4JB9 G;  4XVT G;  3TGT A;  5CAY G;  2NY6 A;  4OM0 G;  4LST G;  4RZ8 A;  4LAJ A;  4LSP G;  4JDT G;  4XVS G;  4YDJ G;  5F4U A;  4JZW A;  2BF1 A;  2I60 G;  2NY1 A;  4DVV A;  4RX4 E;  4KA2 A;  1G9N G;  4OM1 G;  4DKR A;  2NY0 A;  2NY2 A;  5TE7 G;  4DKV A;  4K0A A;  4R4N A;  2NY7 G;  4OLX G;  2NY5 G;  3LQA G;  4DVT A;  5KJR G;  4XNY G;  4YE4 G;  5I9Q A;  4XMP G;  3TGS A;  4DVS A;  4LSV G;  4P9H G; 
#chains in the Genus database with same CATH topology
 4LSU G;  1G9M G;  4DKU A;  5F4R A;  3TGR A;  5T33 G;  2NXY A;  4JPV G;  1GC1 G;  4OLU G;  4YDI G;  3TGQ A;  4JZZ A;  5TE6 G;  4H8W G;  4LSQ G;  4LSR G;  4OLY G;  3SE9 G;  2QAD A;  4RFO G;  4OLW G;  4DKP A;  4YFL E;  1YYL G;  5FEC C;  5FA2 A;  2NY3 A;  4OLZ G;  4YDK G;  2NY4 A;  1RZJ G;  1RZK G;  4R2G A;  4RWY A;  4I54 A;  3RJQ A;  2NXZ A;  4J6R G;  3SE8 G;  5F9O G;  5F4L A;  3U7Y G;  2I5Y G;  5IGX G;  4I53 A;  3JWO A;  3IDX G;  3TIH A;  3JWD A;  4JM2 E;  4R4F A;  4S1Q G;  5F4P A;  4DVR G;  2B4C G;  4XNZ A;  3FUS A;  3HI1 G;  4JKP G;  4OLV G;  5F9W A;  5CD5 A;  4S1R G;  1YYM G;  4RFN A;  4DKO A;  4DVW A;  5F96 G;  4DKQ A;  4JPW G;  4YDL A;  3IDY A;  4LSS G;  4S1S G;  5TE4 G;  4DVX A;  3NGB A;  4JB9 G;  4XVT G;  3TGT A;  5CAY G;  2NY6 A;  4OM0 G;  4LST G;  4RZ8 A;  4LAJ A;  4LSP G;  4JDT G;  4XVS G;  4YDJ G;  5F4U A;  4JZW A;  2BF1 A;  2I60 G;  2NY1 A;  4DVV A;  4RX4 E;  4KA2 A;  1G9N G;  4OM1 G;  4DKR A;  2NY0 A;  2NY2 A;  5TE7 G;  4DKV A;  4K0A A;  4R4N A;  2NY7 G;  4OLX G;  2NY5 G;  3LQA G;  4DVT A;  5KJR G;  4XNY G;  4YE4 G;  5I9Q A;  4XMP G;  3TGS A;  4DVS A;  4LSV G;  4P9H G; 
#chains in the Genus database with same CATH homology
 4LSU G;  1G9M G;  4DKU A;  5F4R A;  3TGR A;  5T33 G;  2NXY A;  4JPV G;  1GC1 G;  4OLU G;  4YDI G;  3TGQ A;  4JZZ A;  5TE6 G;  4H8W G;  4LSQ G;  4LSR G;  4OLY G;  3SE9 G;  2QAD A;  4RFO G;  4OLW G;  4DKP A;  4YFL E;  1YYL G;  5FEC C;  5FA2 A;  2NY3 A;  4OLZ G;  4YDK G;  2NY4 A;  1RZJ G;  1RZK G;  4R2G A;  4RWY A;  4I54 A;  3RJQ A;  2NXZ A;  4J6R G;  3SE8 G;  5F9O G;  5F4L A;  3U7Y G;  2I5Y G;  5IGX G;  4I53 A;  3JWO A;  3IDX G;  3TIH A;  3JWD A;  4JM2 E;  4R4F A;  4S1Q G;  5F4P A;  4DVR G;  2B4C G;  4XNZ A;  3FUS A;  3HI1 G;  4JKP G;  4OLV G;  5F9W A;  5CD5 A;  4S1R G;  1YYM G;  4RFN A;  4DKO A;  4DVW A;  5F96 G;  4DKQ A;  4JPW G;  4YDL A;  3IDY A;  4LSS G;  4S1S G;  5TE4 G;  4DVX A;  3NGB A;  4JB9 G;  4XVT G;  3TGT A;  5CAY G;  2NY6 A;  4OM0 G;  4LST G;  4RZ8 A;  4LAJ A;  4LSP G;  4JDT G;  4XVS G;  4YDJ G;  5F4U A;  4JZW A;  2BF1 A;  2I60 G;  2NY1 A;  4DVV A;  4RX4 E;  4KA2 A;  1G9N G;  4OM1 G;  4DKR A;  2NY0 A;  2NY2 A;  5TE7 G;  4DKV A;  4K0A A;  4R4N A;  2NY7 G;  4OLX G;  2NY5 G;  3LQA G;  4DVT A;  5KJR G;  4XNY G;  4YE4 G;  5I9Q A;  4XMP G;  3TGS A;  4DVS A;  4LSV G;  4P9H G; 
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similar chains in the pdb database (?% sequence similarity)

 
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