5G3MA

Discovery of a novel secreted phospholipase a2 (spla2) inhibitor.
Total Genus 42

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
123
structure length
123
Chain Sequence
GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTI2 (60-63)AH1 (2-12)TI1 (59-62)S2 (73-77)3H1 (17-20)TVIII1 (20-23)O2 (25-115)TII1 (107-110)TIV1 (24-27)O1 (11-69)3H2 (105-107)TII'1 (23-26)AH2 (38-56)3H3 (112-114)O5 (48-122)AH3 (82-100)TIV2 (69-72)S1 (66-70)Updating...
connected with : NaN
molecule tags Hydrolase
source organism Homo sapiens
publication title Discovery of Azd2716: A Novel Secreted Phospholipase A2 (Spla2) Inhibitor for the Treatment of Coronary Artery Disease
pubmed doi rcsb
molecule keywords GROUP 10 SECRETORY PHOSPHOLIPASE A2
total genus 42
structure length 123
sequence length 123
chains with identical sequence B
ec nomenclature ec 3.1.1.4: Phospholipase A(2).
pdb deposition date 2016-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00068 Phospholip_A2_1 Phospholipase A2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.90.10 Mainly Alpha Up-down Bundle Phospholipase A2 Phospholipase A2 domain 5g3mA00
1JQ8A 1IRBA 1JLTA 1JQ9A 2PYCA 1CLPA 1POCA 1LN8A 1POAA 1TG4A 1A3DA 1MKUA 1MH2A 1DCYA 1O3WA 1AYPA 1BP2A 1MH8A 3FO7A 2BP2A 4YV5A 1G0ZA 1JIAA 2ZP5A 1OYFA 1N28A 2PB8A 2PWSA 4H0SA 2AOZA 1N29A 1FAZA 2QU9A 1PPAA 4QEMA 3HZWA 1G2XA 1TP2A 3H1XA 1B4WA 4NTYC 1FX9A 4P2PA 1JLTB 1PWOA 2OQDA 1POBA 1S8HA 4YU7A 1XXWA 2ZP3A 1ZYXA 3MLMA 2B01A 1VKQA 1OWSA 1MH2B 1KPMA 4EIXA 1MG6A 1Y75A 1FB2A 3I3HA 1SV3A 3VBZA 2DO2A 1MKTA 2G58A 1OYFB 1PSJA 1U4JA 1S6BA 2Q1PA 2DPZA 2OTHA 3FVIA 3P2PA 1TJ9A 1VIPA 1TK4A 3U8HA 2PVTA 1CL5A 2WG9A 2OYFA 2GNSA 2OK9A 1XXWB 1KVYA 3ELOA 2O1NA 1OWSB 2B96A 1RGBA 1Y75B 4FGAA 3CXIA 1PIRA 1UMVX 1ZM6A 1S6BB 3HSWA 1OXRA 3UX7A 1FV0A 4GFYA 2Q2JA 2H8IA 1M8SA 1OZYA 1BJJA 4GLDA 1M8RA 4WTBA 1BK9A 3BJWA 2ZBHA 3V9MA 2WQ5A 1BUNA 1AE7A 2OSNA 3U8BA 1ZL7A 1VL9A 1P2PA 2ZP4A 3VC0A 4AUPA 1KVWA 1GMZA 1MKSA 2NOTA 4E4CA 1MH7A 2QHWA 1POEA 2OSHA 3I03A 1A3FA 3T0RA 5G3NA 2QVDA 2AZYA 1PA0A 4UY1A 1SZ8A 2H4CA 1Q7AA 2I0UA 1UNEA 4DCFA 1OQSA 2RD4A 1PISA 3NJUA 3HZDA 4QF7A 1XXSA 1Y4LA 3FVJA 1HN4A 1TDVA 2PMJA 1IJLA 2FNXA 4O1YA 1YXHA 2B03A 4HMBA 2B04A 2OTFA 3GCIA 1GODA 1QLLA 3Q4YA 1J1AA 1PC9A 5P2PA 3G8HA 2H4CB 4NTXC 1KQUA 1FXFA 2PHIA 3QLMA 1OQSB 1S8IA 2RD4B 4HG9A 1TGMA 1OXLA 1LE7A 4K06A 4DBKA 4RFPA 1TH6A 1Z76A 3O4MA 1KVXA 1MF4A 3CBIA 1C1JA 1PSHA 1MKVA 1PO8A 1IT5A 2BAXA 1LWBA 3IQ3A 1FDKA 1TC8A 1YXLA 2B00A 1S8GA 1SXKA 1DB5A 1AOKA 3I3IA 2OLIA 1SQZA 1DB4A 3R0LD 2BCHA 1IT4A 1KP4A 1Y6OA 4QERA 3U8IA 3L30A 3U8DA 4G5IA 4YZ7A 2ARMA 1O2EA 4QF8A 1PODA 1BBCA 1CEHA 3JQ5A 1Q6VA 1Y38A 1OZ6A 1TG1A 1SKGA 3QNLA 3G8GA 4K09A 4BP2A 2WG8A 1AOKB 2QHDA 1A2AA 4KF3A 1FE5A 2QOGA 1BVMA 1TJKA 1ZWPA 2BPPA 1U73A 1SFWA 1GH4A 2WG7A 5G3MA 1C74A 3JQLA 1T37A 1LE6A 1SFVA 1VPIA 2AZZA 2B17A 1Q5TA 3BP2A 1G4IA 3OSHA 1SV9A 4NTWC 3JR8A 2BD1A 3FG5A 1VAPA 1L8SA 1Y6PA 3G8FA 2WG8B 1ZLBA 1KVOA 4QMCA 1TD7A 3CYLA 3DIHA 2QOGB 1GP7A 2QHEA 2PH4A 2OUBA 3JTIA 1BPQA 1M8TA 4QGDA 1P7OA 1ZR8A 1DPYA 1PP2L 2QUEA 1MC2A
chains in the Genus database with same CATH superfamily
1JQ8A 1IRBA 1JLTA 1JQ9A 2PYCA 1CLPA 1POCA 1LN8A 1POAA 1TG4A 1A3DA 1MKUA 1MH2A 1DCYA 1O3WA 1AYPA 1BP2A 1MH8A 3FO7A 2BP2A 4YV5A 1G0ZA 1JIAA 2ZP5A 1OYFA 1N28A 2PB8A 2PWSA 4H0SA 2AOZA 1N29A 1FAZA 2QU9A 1PPAA 4QEMA 3HZWA 1G2XA 1TP2A 3H1XA 1B4WA 4NTYC 1FX9A 4P2PA 1JLTB 1PWOA 2OQDA 1POBA 1S8HA 4YU7A 1XXWA 2ZP3A 1ZYXA 3MLMA 2B01A 1VKQA 1OWSA 1MH2B 1KPMA 4EIXA 1MG6A 1Y75A 1FB2A 3I3HA 1SV3A 3VBZA 2DO2A 1MKTA 2G58A 1OYFB 1PSJA 1U4JA 1S6BA 2Q1PA 2DPZA 2OTHA 3FVIA 3P2PA 1TJ9A 1VIPA 1TK4A 3U8HA 2PVTA 1CL5A 2WG9A 2OYFA 2GNSA 2OK9A 1XXWB 1KVYA 3ELOA 2O1NA 1OWSB 2B96A 1RGBA 1Y75B 4FGAA 3CXIA 1PIRA 1UMVX 1ZM6A 1S6BB 3HSWA 1OXRA 3UX7A 1FV0A 4GFYA 2Q2JA 2H8IA 1M8SA 1OZYA 1BJJA 4GLDA 1M8RA 4WTBA 1BK9A 3BJWA 2ZBHA 3V9MA 2WQ5A 1BUNA 1AE7A 2OSNA 3U8BA 1ZL7A 1VL9A 1P2PA 2ZP4A 3VC0A 4AUPA 1KVWA 1GMZA 1MKSA 2NOTA 4E4CA 1MH7A 2QHWA 1POEA 2OSHA 3I03A 1A3FA 3T0RA 5G3NA 2QVDA 2AZYA 1PA0A 4UY1A 1SZ8A 2H4CA 1Q7AA 2I0UA 1UNEA 4DCFA 1OQSA 2RD4A 1PISA 3NJUA 3HZDA 4QF7A 1XXSA 1Y4LA 3FVJA 1HN4A 1TDVA 2PMJA 1IJLA 2FNXA 4O1YA 1YXHA 2B03A 4HMBA 2B04A 2OTFA 3GCIA 1GODA 1QLLA 3Q4YA 1J1AA 1PC9A 5P2PA 3G8HA 2H4CB 4NTXC 1KQUA 1FXFA 2PHIA 3QLMA 1OQSB 1S8IA 2RD4B 4HG9A 1TGMA 1OXLA 1LE7A 4K06A 4DBKA 4RFPA 1TH6A 1Z76A 3O4MA 1KVXA 1MF4A 3CBIA 1C1JA 1PSHA 1MKVA 1PO8A 1IT5A 2BAXA 1LWBA 3IQ3A 1FDKA 1TC8A 1YXLA 2B00A 1S8GA 1SXKA 1DB5A 1AOKA 3I3IA 2OLIA 1SQZA 1DB4A 3R0LD 2BCHA 1IT4A 1KP4A 1Y6OA 4QERA 3U8IA 3L30A 3U8DA 4G5IA 4YZ7A 2ARMA 1O2EA 4QF8A 1PODA 1BBCA 1CEHA 3JQ5A 1Q6VA 1Y38A 1OZ6A 1TG1A 1SKGA 3QNLA 3G8GA 4K09A 4BP2A 2WG8A 1AOKB 2QHDA 1A2AA 4KF3A 1FE5A 2QOGA 1BVMA 1TJKA 1ZWPA 2BPPA 1U73A 1SFWA 1GH4A 2WG7A 5G3MA 1C74A 3JQLA 1T37A 1LE6A 1SFVA 1VPIA 2AZZA 2B17A 1Q5TA 3BP2A 1G4IA 3OSHA 1SV9A 4NTWC 3JR8A 2BD1A 3FG5A 1VAPA 1L8SA 1Y6PA 3G8FA 2WG8B 1ZLBA 1KVOA 4QMCA 1TD7A 3CYLA 3DIHA 2QOGB 1GP7A 2QHEA 2PH4A 2OUBA 3JTIA 1BPQA 1M8TA 4QGDA 1P7OA 1ZR8A 1DPYA 1PP2L 2QUEA 1MC2A
chains in the Genus database with same CATH topology
1JQ8A 1IRBA 1JLTA 1JQ9A 2PYCA 1CLPA 1POCA 1LN8A 1POAA 1TG4A 1A3DA 1MKUA 1MH2A 1DCYA 1O3WA 1AYPA 1BP2A 1MH8A 3FO7A 2BP2A 4YV5A 1G0ZA 1JIAA 2ZP5A 1OYFA 1N28A 2PB8A 2PWSA 4H0SA 2AOZA 1N29A 1FAZA 2QU9A 1PPAA 4QEMA 3HZWA 1G2XA 1TP2A 3H1XA 1B4WA 4NTYC 1FX9A 4P2PA 1JLTB 1PWOA 2OQDA 1POBA 1S8HA 4YU7A 1XXWA 2ZP3A 1ZYXA 3MLMA 2B01A 1VKQA 1OWSA 1MH2B 1KPMA 4EIXA 1MG6A 1Y75A 1FB2A 3I3HA 1SV3A 3VBZA 2DO2A 1MKTA 2G58A 1OYFB 1PSJA 1U4JA 1S6BA 2Q1PA 2DPZA 2OTHA 3FVIA 3P2PA 1TJ9A 1VIPA 1TK4A 3U8HA 2PVTA 1CL5A 2WG9A 2OYFA 2GNSA 2OK9A 1XXWB 1KVYA 3ELOA 2O1NA 1OWSB 2B96A 1RGBA 1Y75B 4FGAA 3CXIA 1PIRA 1UMVX 1ZM6A 1S6BB 3HSWA 1OXRA 3UX7A 1FV0A 4GFYA 2Q2JA 2H8IA 1M8SA 1OZYA 1BJJA 4GLDA 1M8RA 4WTBA 1BK9A 3BJWA 2ZBHA 3V9MA 2WQ5A 1BUNA 1AE7A 2OSNA 3U8BA 1ZL7A 1VL9A 1P2PA 2ZP4A 3VC0A 4AUPA 1KVWA 1GMZA 1MKSA 2NOTA 4E4CA 1MH7A 2QHWA 1POEA 2OSHA 3I03A 1A3FA 3T0RA 5G3NA 2QVDA 2AZYA 1PA0A 4UY1A 1SZ8A 2H4CA 1Q7AA 2I0UA 1UNEA 4DCFA 1OQSA 2RD4A 1PISA 3NJUA 3HZDA 4QF7A 1XXSA 1Y4LA 3FVJA 1HN4A 1TDVA 2PMJA 1IJLA 2FNXA 4O1YA 1YXHA 2B03A 4HMBA 2B04A 2OTFA 3GCIA 1GODA 1QLLA 3Q4YA 1J1AA 1PC9A 5P2PA 3G8HA 2H4CB 4NTXC 1KQUA 1FXFA 2PHIA 3QLMA 1OQSB 1S8IA 2RD4B 4HG9A 1TGMA 1OXLA 1LE7A 4K06A 4DBKA 4RFPA 1TH6A 1Z76A 3O4MA 1KVXA 1MF4A 3CBIA 1C1JA 1PSHA 1MKVA 1PO8A 1IT5A 2BAXA 1LWBA 3IQ3A 1FDKA 1TC8A 1YXLA 2B00A 1S8GA 1SXKA 1DB5A 1AOKA 3I3IA 2OLIA 1SQZA 1DB4A 3R0LD 2BCHA 1IT4A 1KP4A 1Y6OA 4QERA 3U8IA 3L30A 3U8DA 4G5IA 4YZ7A 2ARMA 1O2EA 4QF8A 1PODA 1BBCA 1CEHA 3JQ5A 1Q6VA 1Y38A 1OZ6A 1TG1A 1SKGA 3QNLA 3G8GA 4K09A 4BP2A 2WG8A 1AOKB 2QHDA 1A2AA 4KF3A 1FE5A 2QOGA 1BVMA 1TJKA 1ZWPA 2BPPA 1U73A 1SFWA 1GH4A 2WG7A 5G3MA 1C74A 3JQLA 1T37A 1LE6A 1SFVA 1VPIA 2AZZA 2B17A 1Q5TA 3BP2A 1G4IA 3OSHA 1SV9A 4NTWC 3JR8A 2BD1A 3FG5A 1VAPA 1L8SA 1Y6PA 3G8FA 2WG8B 1ZLBA 1KVOA 4QMCA 1TD7A 3CYLA 3DIHA 2QOGB 1GP7A 2QHEA 2PH4A 2OUBA 3JTIA 1BPQA 1M8TA 4QGDA 1P7OA 1ZR8A 1DPYA 1PP2L 2QUEA 1MC2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JQ8 A;  1IRB A;  1JLT A;  1JQ9 A;  2PYC A;  1CLP A;  1POC A;  1LN8 A;  1POA A;  1TG4 A;  1A3D A;  1MKU A;  1MH2 A;  1DCY A;  1O3W A;  1AYP A;  1BP2 A;  1MH8 A;  3FO7 A;  2BP2 A;  4YV5 A;  1G0Z A;  1JIA A;  2ZP5 A;  1OYF A;  1N28 A;  2PB8 A;  2PWS A;  4H0S A;  2AOZ A;  1N29 A;  1FAZ A;  2QU9 A;  1PPA A;  4QEM A;  3HZW A;  1G2X A;  1TP2 A;  3H1X A;  1B4W A;  4NTY C;  1FX9 A;  4P2P A;  1JLT B;  1PWO A;  2OQD A;  1POB A;  1S8H A;  4YU7 A;  1XXW A;  2ZP3 A;  1ZYX A;  3MLM A;  2B01 A;  1VKQ A;  1OWS A;  1MH2 B;  1KPM A;  4EIX A;  1MG6 A;  1Y75 A;  1FB2 A;  3I3H A;  1SV3 A;  3VBZ A;  2DO2 A;  1MKT A;  2G58 A;  1OYF B;  1PSJ A;  1U4J A;  1S6B A;  2Q1P A;  2DPZ A;  2OTH A;  3FVI A;  3P2P A;  1TJ9 A;  1VIP A;  1TK4 A;  3U8H A;  2PVT A;  1CL5 A;  2WG9 A;  2OYF A;  2GNS A;  2OK9 A;  1XXW B;  1KVY A;  3ELO A;  2O1N A;  1OWS B;  2B96 A;  1RGB A;  1Y75 B;  4FGA A;  3CXI A;  1PIR A;  1UMV X;  1ZM6 A;  1S6B B;  3HSW A;  1OXR A;  3UX7 A;  1FV0 A;  4GFY A;  2Q2J A;  2H8I A;  1M8S A;  1OZY A;  1BJJ A;  4GLD A;  1M8R A;  4WTB A;  1BK9 A;  3BJW A;  2ZBH A;  3V9M A;  2WQ5 A;  1BUN A;  1AE7 A;  2OSN A;  3U8B A;  1ZL7 A;  1VL9 A;  1P2P A;  2ZP4 A;  3VC0 A;  4AUP A;  1KVW A;  1GMZ A;  1MKS A;  2NOT A;  4E4C A;  1MH7 A;  2QHW A;  1POE A;  2OSH A;  3I03 A;  1A3F A;  3T0R A;  5G3N A;  2QVD A;  2AZY A;  1PA0 A;  4UY1 A;  1SZ8 A;  2H4C A;  1Q7A A;  2I0U A;  1UNE A;  4DCF A;  1OQS A;  2RD4 A;  1PIS A;  3NJU A;  3HZD A;  4QF7 A;  1XXS A;  1Y4L A;  3FVJ A;  1HN4 A;  1TDV A;  2PMJ A;  1IJL A;  2FNX A;  4O1Y A;  1YXH A;  2B03 A;  4HMB A;  2B04 A;  2OTF A;  3GCI A;  1GOD A;  1QLL A;  3Q4Y A;  1J1A A;  1PC9 A;  5P2P A;  3G8H A;  2H4C B;  4NTX C;  1KQU A;  1FXF A;  2PHI A;  3QLM A;  1OQS B;  1S8I A;  2RD4 B;  4HG9 A;  1TGM A;  1OXL A;  1LE7 A;  4K06 A;  4DBK A;  4RFP A;  1TH6 A;  1Z76 A;  3O4M A;  1KVX A;  1MF4 A;  3CBI A;  1C1J A;  1PSH A;  1MKV A;  1PO8 A;  1IT5 A;  2BAX A;  1LWB A;  3IQ3 A;  1FDK A;  1TC8 A;  1YXL A;  2B00 A;  1S8G A;  1SXK A;  1DB5 A;  1AOK A;  3I3I A;  2OLI A;  1SQZ A;  1DB4 A;  3R0L D;  2BCH A;  1IT4 A;  1KP4 A;  1Y6O A;  4QER A;  3U8I A;  3L30 A;  3U8D A;  4G5I A;  4YZ7 A;  2ARM A;  1O2E A;  4QF8 A;  1POD A;  1BBC A;  1CEH A;  3JQ5 A;  1Q6V A;  1Y38 A;  1OZ6 A;  1TG1 A;  1SKG A;  3QNL A;  3G8G A;  4K09 A;  4BP2 A;  2WG8 A;  1AOK B;  2QHD A;  1A2A A;  4KF3 A;  1FE5 A;  2QOG A;  1BVM A;  1TJK A;  1ZWP A;  2BPP A;  1U73 A;  1SFW A;  1GH4 A;  2WG7 A;  5G3M A;  1C74 A;  3JQL A;  1T37 A;  1LE6 A;  1SFV A;  1VPI A;  2AZZ A;  2B17 A;  1Q5T A;  3BP2 A;  1G4I A;  3OSH A;  1SV9 A;  4NTW C;  3JR8 A;  2BD1 A;  3FG5 A;  1VAP A;  1L8S A;  1Y6P A;  3G8F A;  2WG8 B;  1ZLB A;  1KVO A;  4QMC A;  1TD7 A;  3CYL A;  3DIH A;  2QOG B;  1GP7 A;  2QHE A;  2PH4 A;  2OUB A;  3JTI A;  1BPQ A;  1M8T A;  4QGD A;  1P7O A;  1ZR8 A;  1DPY A;  1PP2 L;  2QUE A;  1MC2 A; 
#chains in the Genus database with same CATH topology
 1JQ8 A;  1IRB A;  1JLT A;  1JQ9 A;  2PYC A;  1CLP A;  1POC A;  1LN8 A;  1POA A;  1TG4 A;  1A3D A;  1MKU A;  1MH2 A;  1DCY A;  1O3W A;  1AYP A;  1BP2 A;  1MH8 A;  3FO7 A;  2BP2 A;  4YV5 A;  1G0Z A;  1JIA A;  2ZP5 A;  1OYF A;  1N28 A;  2PB8 A;  2PWS A;  4H0S A;  2AOZ A;  1N29 A;  1FAZ A;  2QU9 A;  1PPA A;  4QEM A;  3HZW A;  1G2X A;  1TP2 A;  3H1X A;  1B4W A;  4NTY C;  1FX9 A;  4P2P A;  1JLT B;  1PWO A;  2OQD A;  1POB A;  1S8H A;  4YU7 A;  1XXW A;  2ZP3 A;  1ZYX A;  3MLM A;  2B01 A;  1VKQ A;  1OWS A;  1MH2 B;  1KPM A;  4EIX A;  1MG6 A;  1Y75 A;  1FB2 A;  3I3H A;  1SV3 A;  3VBZ A;  2DO2 A;  1MKT A;  2G58 A;  1OYF B;  1PSJ A;  1U4J A;  1S6B A;  2Q1P A;  2DPZ A;  2OTH A;  3FVI A;  3P2P A;  1TJ9 A;  1VIP A;  1TK4 A;  3U8H A;  2PVT A;  1CL5 A;  2WG9 A;  2OYF A;  2GNS A;  2OK9 A;  1XXW B;  1KVY A;  3ELO A;  2O1N A;  1OWS B;  2B96 A;  1RGB A;  1Y75 B;  4FGA A;  3CXI A;  1PIR A;  1UMV X;  1ZM6 A;  1S6B B;  3HSW A;  1OXR A;  3UX7 A;  1FV0 A;  4GFY A;  2Q2J A;  2H8I A;  1M8S A;  1OZY A;  1BJJ A;  4GLD A;  1M8R A;  4WTB A;  1BK9 A;  3BJW A;  2ZBH A;  3V9M A;  2WQ5 A;  1BUN A;  1AE7 A;  2OSN A;  3U8B A;  1ZL7 A;  1VL9 A;  1P2P A;  2ZP4 A;  3VC0 A;  4AUP A;  1KVW A;  1GMZ A;  1MKS A;  2NOT A;  4E4C A;  1MH7 A;  2QHW A;  1POE A;  2OSH A;  3I03 A;  1A3F A;  3T0R A;  5G3N A;  2QVD A;  2AZY A;  1PA0 A;  4UY1 A;  1SZ8 A;  2H4C A;  1Q7A A;  2I0U A;  1UNE A;  4DCF A;  1OQS A;  2RD4 A;  1PIS A;  3NJU A;  3HZD A;  4QF7 A;  1XXS A;  1Y4L A;  3FVJ A;  1HN4 A;  1TDV A;  2PMJ A;  1IJL A;  2FNX A;  4O1Y A;  1YXH A;  2B03 A;  4HMB A;  2B04 A;  2OTF A;  3GCI A;  1GOD A;  1QLL A;  3Q4Y A;  1J1A A;  1PC9 A;  5P2P A;  3G8H A;  2H4C B;  4NTX C;  1KQU A;  1FXF A;  2PHI A;  3QLM A;  1OQS B;  1S8I A;  2RD4 B;  4HG9 A;  1TGM A;  1OXL A;  1LE7 A;  4K06 A;  4DBK A;  4RFP A;  1TH6 A;  1Z76 A;  3O4M A;  1KVX A;  1MF4 A;  3CBI A;  1C1J A;  1PSH A;  1MKV A;  1PO8 A;  1IT5 A;  2BAX A;  1LWB A;  3IQ3 A;  1FDK A;  1TC8 A;  1YXL A;  2B00 A;  1S8G A;  1SXK A;  1DB5 A;  1AOK A;  3I3I A;  2OLI A;  1SQZ A;  1DB4 A;  3R0L D;  2BCH A;  1IT4 A;  1KP4 A;  1Y6O A;  4QER A;  3U8I A;  3L30 A;  3U8D A;  4G5I A;  4YZ7 A;  2ARM A;  1O2E A;  4QF8 A;  1POD A;  1BBC A;  1CEH A;  3JQ5 A;  1Q6V A;  1Y38 A;  1OZ6 A;  1TG1 A;  1SKG A;  3QNL A;  3G8G A;  4K09 A;  4BP2 A;  2WG8 A;  1AOK B;  2QHD A;  1A2A A;  4KF3 A;  1FE5 A;  2QOG A;  1BVM A;  1TJK A;  1ZWP A;  2BPP A;  1U73 A;  1SFW A;  1GH4 A;  2WG7 A;  5G3M A;  1C74 A;  3JQL A;  1T37 A;  1LE6 A;  1SFV A;  1VPI A;  2AZZ A;  2B17 A;  1Q5T A;  3BP2 A;  1G4I A;  3OSH A;  1SV9 A;  4NTW C;  3JR8 A;  2BD1 A;  3FG5 A;  1VAP A;  1L8S A;  1Y6P A;  3G8F A;  2WG8 B;  1ZLB A;  1KVO A;  4QMC A;  1TD7 A;  3CYL A;  3DIH A;  2QOG B;  1GP7 A;  2QHE A;  2PH4 A;  2OUB A;  3JTI A;  1BPQ A;  1M8T A;  4QGD A;  1P7O A;  1ZR8 A;  1DPY A;  1PP2 L;  2QUE A;  1MC2 A; 
#chains in the Genus database with same CATH homology
 1JQ8 A;  1IRB A;  1JLT A;  1JQ9 A;  2PYC A;  1CLP A;  1POC A;  1LN8 A;  1POA A;  1TG4 A;  1A3D A;  1MKU A;  1MH2 A;  1DCY A;  1O3W A;  1AYP A;  1BP2 A;  1MH8 A;  3FO7 A;  2BP2 A;  4YV5 A;  1G0Z A;  1JIA A;  2ZP5 A;  1OYF A;  1N28 A;  2PB8 A;  2PWS A;  4H0S A;  2AOZ A;  1N29 A;  1FAZ A;  2QU9 A;  1PPA A;  4QEM A;  3HZW A;  1G2X A;  1TP2 A;  3H1X A;  1B4W A;  4NTY C;  1FX9 A;  4P2P A;  1JLT B;  1PWO A;  2OQD A;  1POB A;  1S8H A;  4YU7 A;  1XXW A;  2ZP3 A;  1ZYX A;  3MLM A;  2B01 A;  1VKQ A;  1OWS A;  1MH2 B;  1KPM A;  4EIX A;  1MG6 A;  1Y75 A;  1FB2 A;  3I3H A;  1SV3 A;  3VBZ A;  2DO2 A;  1MKT A;  2G58 A;  1OYF B;  1PSJ A;  1U4J A;  1S6B A;  2Q1P A;  2DPZ A;  2OTH A;  3FVI A;  3P2P A;  1TJ9 A;  1VIP A;  1TK4 A;  3U8H A;  2PVT A;  1CL5 A;  2WG9 A;  2OYF A;  2GNS A;  2OK9 A;  1XXW B;  1KVY A;  3ELO A;  2O1N A;  1OWS B;  2B96 A;  1RGB A;  1Y75 B;  4FGA A;  3CXI A;  1PIR A;  1UMV X;  1ZM6 A;  1S6B B;  3HSW A;  1OXR A;  3UX7 A;  1FV0 A;  4GFY A;  2Q2J A;  2H8I A;  1M8S A;  1OZY A;  1BJJ A;  4GLD A;  1M8R A;  4WTB A;  1BK9 A;  3BJW A;  2ZBH A;  3V9M A;  2WQ5 A;  1BUN A;  1AE7 A;  2OSN A;  3U8B A;  1ZL7 A;  1VL9 A;  1P2P A;  2ZP4 A;  3VC0 A;  4AUP A;  1KVW A;  1GMZ A;  1MKS A;  2NOT A;  4E4C A;  1MH7 A;  2QHW A;  1POE A;  2OSH A;  3I03 A;  1A3F A;  3T0R A;  5G3N A;  2QVD A;  2AZY A;  1PA0 A;  4UY1 A;  1SZ8 A;  2H4C A;  1Q7A A;  2I0U A;  1UNE A;  4DCF A;  1OQS A;  2RD4 A;  1PIS A;  3NJU A;  3HZD A;  4QF7 A;  1XXS A;  1Y4L A;  3FVJ A;  1HN4 A;  1TDV A;  2PMJ A;  1IJL A;  2FNX A;  4O1Y A;  1YXH A;  2B03 A;  4HMB A;  2B04 A;  2OTF A;  3GCI A;  1GOD A;  1QLL A;  3Q4Y A;  1J1A A;  1PC9 A;  5P2P A;  3G8H A;  2H4C B;  4NTX C;  1KQU A;  1FXF A;  2PHI A;  3QLM A;  1OQS B;  1S8I A;  2RD4 B;  4HG9 A;  1TGM A;  1OXL A;  1LE7 A;  4K06 A;  4DBK A;  4RFP A;  1TH6 A;  1Z76 A;  3O4M A;  1KVX A;  1MF4 A;  3CBI A;  1C1J A;  1PSH A;  1MKV A;  1PO8 A;  1IT5 A;  2BAX A;  1LWB A;  3IQ3 A;  1FDK A;  1TC8 A;  1YXL A;  2B00 A;  1S8G A;  1SXK A;  1DB5 A;  1AOK A;  3I3I A;  2OLI A;  1SQZ A;  1DB4 A;  3R0L D;  2BCH A;  1IT4 A;  1KP4 A;  1Y6O A;  4QER A;  3U8I A;  3L30 A;  3U8D A;  4G5I A;  4YZ7 A;  2ARM A;  1O2E A;  4QF8 A;  1POD A;  1BBC A;  1CEH A;  3JQ5 A;  1Q6V A;  1Y38 A;  1OZ6 A;  1TG1 A;  1SKG A;  3QNL A;  3G8G A;  4K09 A;  4BP2 A;  2WG8 A;  1AOK B;  2QHD A;  1A2A A;  4KF3 A;  1FE5 A;  2QOG A;  1BVM A;  1TJK A;  1ZWP A;  2BPP A;  1U73 A;  1SFW A;  1GH4 A;  2WG7 A;  5G3M A;  1C74 A;  3JQL A;  1T37 A;  1LE6 A;  1SFV A;  1VPI A;  2AZZ A;  2B17 A;  1Q5T A;  3BP2 A;  1G4I A;  3OSH A;  1SV9 A;  4NTW C;  3JR8 A;  2BD1 A;  3FG5 A;  1VAP A;  1L8S A;  1Y6P A;  3G8F A;  2WG8 B;  1ZLB A;  1KVO A;  4QMC A;  1TD7 A;  3CYL A;  3DIH A;  2QOG B;  1GP7 A;  2QHE A;  2PH4 A;  2OUB A;  3JTI A;  1BPQ A;  1M8T A;  4QGD A;  1P7O A;  1ZR8 A;  1DPY A;  1PP2 L;  2QUE A;  1MC2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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