5HOCA

P73 homo-tetramerization domain mutant ii
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
44
structure length
44
Chain Sequence
TYYLQVRGRRNFEILMELKRSLELMELVPQPLVDSYDQQQQLLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Tumor protein p73
total genus 15
structure length 44
sequence length 44
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-01-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.170.10 Few Secondary Structures Irregular p53, subunit A p53-like tetramerisation domain 5hocA00
2WQIA 5HOCA 1SAEA 2MW4A 1OLHA 1SALA 2KBYA 3SAKA 1SAKA 2WTTA 1OLGA 3ZY1A 5HOBA 4A9ZA 1SAFA
chains in the Genus database with same CATH superfamily
2WQIA 5HOCA 1SAEA 2MW4A 1OLHA 1SALA 2KBYA 3SAKA 1SAKA 2WTTA 1OLGA 3ZY1A 5HOBA 4A9ZA 1SAFA
chains in the Genus database with same CATH topology
2WQIA 5HOCA 1SAEA 2MW4A 1OLHA 1SALA 2KBYA 3SAKA 1SAKA 2WTTA 1OLGA 3ZY1A 5HOBA 4A9ZA 1SAFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WQI A;  5HOC A;  1SAE A;  2MW4 A;  1OLH A;  1SAL A;  2KBY A;  3SAK A;  1SAK A;  2WTT A;  1OLG A;  3ZY1 A;  5HOB A;  4A9Z A;  1SAF A; 
#chains in the Genus database with same CATH topology
 2WQI A;  5HOC A;  1SAE A;  2MW4 A;  1OLH A;  1SAL A;  2KBY A;  3SAK A;  1SAK A;  2WTT A;  1OLG A;  3ZY1 A;  5HOB A;  4A9Z A;  1SAF A; 
#chains in the Genus database with same CATH homology
 2WQI A;  5HOC A;  1SAE A;  2MW4 A;  1OLH A;  1SAL A;  2KBY A;  3SAK A;  1SAK A;  2WTT A;  1OLG A;  3ZY1 A;  5HOB A;  4A9Z A;  1SAF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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