5HY7A

Sf3b10-sf3b130 from chaetomium thermophilum
Total Genus 244
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
244
sequence length
1207
structure length
1173
Chain Sequence
NMFLYSLTIQPPTTITQALLGQFSGTKEQQIITASGSRLTLLQPDPRQGKVNTIVSHDIFGIIRAMAAFRLAGSHKDYIILATDSGRIAIIEYLPKENRFQRIHLETFGKSGVRRVIPGQYLAADPKGRACLIASVEKNKLVYVLNRNAQAELTISSPLEAHKPGVIVLSLVALDVGYSNPVFAALEYEYSEADQDPTGQAAKQLEMQLVYYELDLGLNHVVRKWSDTVDPTSSLLFQVPGGNDGPSGVLVCGEENITYRHSNQEAFRVPIPRRRGATEDPNRKRTIVAGVMHKLKGSAGAFFFLLQTEDGDLFKVTIDMVEDEKGNPTGEVKRVKIKYFDTVPIAHSLCILKSGFLFVASEFGNHHFYQFEKLGDDDDEPEFTSDDFPADWNAPYNPVYFKPRPLENLVLVESIDSMNPLVGCKVANLTGEDAPQIYAICGNGARSSFRMLKHGLEVSEIVASELPGTPSAVWTTKLTKYDEYDAYIVLSFTNATLVLSIGETVEEVSDSGFLTTVPTLAVQQMGEEGLIQIHPKGIRHIVQGRVNEWPAPQHRSIVAATTNENQVVIALSSGEIVYFEMDADGSLAEYDEKKQMSGTVTSLSLGKVPEGLRRSSFLAVGCDDCTVRILSLDPESTLEMKSIQALTAAPSSLLIMSMEDSTGGTTLYLHIGLHSGVYLRTVLDEITGELTDTRQKFLGPKPTKLFQVTVQNQTCVLALSSRPWLGYTAPITRNFVMTPLSYTELGYTWSFNSEQCQEGMVGIHANYLRIFTIEKLGQTMIQKSCPLTYTPKRLVKHPEQPYFYVIEADNNTLPPELVLPPEDFGYPKARGRWASCIEIVDPVSEEQPRVLKRIELEGNEAAVSAAVVPFASQDGESFLIVGTGKDMVLNPRASTEGAIHVYRFIDDGRDLEFIHKTIIEEPPLAFCPFQGRLLAGIGKMLRIYDLGLKQLLRKAQAEVSPQLIVSLDTRHNRIVVGDVQHGMTYVVYKPDSNKLIPFADDTIARWTTCTTMVDYESVAGGDKFGNLWIVRCPERASLESAPNRLDLMAHFYPQDLPTSICKTNLVVGGQDVLVWSGIQGTVGVLIPFVTREDADFFQNLESHMRAEDPPLAGRDHLIYRGYYVPVKGVIDGDLCERFTLLPNDKKQMIAGELDRSVREIERKISDIRTRSAF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
pubmed doi rcsb
molecule tags Protein binding
source organism Chaetomium thermophilum var. thermophilum dsm 1495
molecule keywords Putative pre-mRNA splicing protein
total genus 244
structure length 1173
sequence length 1207
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03178 CPSF_A CPSF A subunit region
A PF10433 MMS1_N Mono-functional DNA-alkylating methyl methanesulfonate N-term
Image from the rcsb pdb (www.rcsb.org)
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