5IGXG

Crystal structure of nih45-46 fab germline precursor in complex with 426c.tm1deltav1-3 gp120
Total Genus 74
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
344
structure length
334
Chain Sequence
VWKEAKTTLFCASDAKAYEKECHNVWATHACVPTDPNPQEVVLENVTENFNMWKNDMVDQMQEDVISIWDQCLKPCVKLTNTSTLTQACPKVTFDPIPIHYCAPAGYAILKCNNKTFNGKGPCNNVSTVQCTHGIKPVVSTQLLLNGSLAEEEIVIRSKDLSDNAKIIIVQLNKSVEIVCTRPNDIRQAYCNISGRNWSEAVNQVKKKLKEHFPHKNISFQSSSGGDLEITTHSFNCGGEFFYCNTSGLFNDTISNATIMLPCRIKQIINMWQEVGKAIYAPPIKGNITCKSDITGLLLLRDGGDTNTEIFRPGGGDMRDNWRSELYKYKVVEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis for germline antibody recognition of HIV-1 immunogens.
pubmed doi rcsb
molecule tags Immune system
source organism Human immunodeficiency virus 1
molecule keywords 426c.TM1deltaV1-3 gp120
total genus 74
structure length 334
sequence length 344
ec nomenclature
pdb deposition date 2016-02-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 5igxG01
2QADA 4K0AA 4S1RG 3TGRA 3SE9G 4OM0G 1G9MG 4LSTG 4YFLE 4DVSA 3HI1G 5FA2A 2NY6A 4RFOG 5TE7G 4DKUA 4OLZG 3FUSA 5TE6G 5I9QA 3U7YG 4DVTA 3IDXG 3TGSA 2NY0A 4KA2A 4J6RG 4LSVG 4R4FA 5F9WA 4JPVG 1G9NG 5FECC 4DKOA 4DKVA 4LSUG 1RZJG 4S1QG 4XMPG 4XNYG 4XVSG 4DKQA 3SE8G 3IDYA 4DVWA 4I54A 5TE4G 4OLXG 4H8WG 4LAJA 2NY2A 1GC1G 3TGQA 5T33G 2NY4A 4LSRG 4YDKG 3RJQA 4OLVG 4DVVA 5F96G 2NXZA 4RWYA 4DKPA 1RZKG 4XNZA 5F4PA 4OLYG 2I60G 4JZZA 4LSQG 4JPWG 4JZWA 2B4CG 5CD5A 4S1SG 3JWOA 2NY5G 3TIHA 4I53A 2NY1A 4DVRG 4LSPG 5IGXG 2BF1A 4YE4G 4DVXA 5F4LA 4P9HG 4RFNA 3JWDA 4YDIG 2NXYA 5CAYG 4LSSG 4YDLA 4RX4E 4XVTG 3LQAG 4OLUG 4OLWG 1YYMG 1YYLG 2NY3A 5F4RA 4DKRA 4JB9G 3NGBA 5F4UA 4JKPG 4R2GA 5F9OG 2I5YG 4JDTG 2NY7G 4OM1G 4R4NA 3TGTA 4YDJG 4JM2E 4RZ8A 5KJRG
chains in the Genus database with same CATH superfamily
2QADA 4K0AA 4S1RG 3TGRA 3SE9G 4OM0G 1G9MG 4LSTG 4YFLE 4DVSA 3HI1G 5FA2A 2NY6A 4RFOG 5TE7G 4DKUA 4OLZG 3FUSA 5TE6G 5I9QA 3U7YG 4DVTA 3IDXG 3TGSA 2NY0A 4KA2A 4J6RG 4LSVG 4R4FA 5F9WA 4JPVG 1G9NG 5FECC 4DKOA 4DKVA 4LSUG 1RZJG 4S1QG 4XMPG 4XNYG 4XVSG 4DKQA 3SE8G 3IDYA 4DVWA 4I54A 5TE4G 4OLXG 4H8WG 4LAJA 2NY2A 1GC1G 3TGQA 5T33G 2NY4A 4LSRG 4YDKG 3RJQA 4OLVG 4DVVA 5F96G 2NXZA 4RWYA 4DKPA 1RZKG 4XNZA 5F4PA 4OLYG 2I60G 4JZZA 4LSQG 4JPWG 4JZWA 2B4CG 5CD5A 4S1SG 3JWOA 2NY5G 3TIHA 4I53A 2NY1A 4DVRG 4LSPG 5IGXG 2BF1A 4YE4G 4DVXA 5F4LA 4P9HG 4RFNA 3JWDA 4YDIG 2NXYA 5CAYG 4LSSG 4YDLA 4RX4E 4XVTG 3LQAG 4OLUG 4OLWG 1YYMG 1YYLG 2NY3A 5F4RA 4DKRA 4JB9G 3NGBA 5F4UA 4JKPG 4R2GA 5F9OG 2I5YG 4JDTG 2NY7G 4OM1G 4R4NA 3TGTA 4YDJG 4JM2E 4RZ8A 5KJRG
chains in the Genus database with same CATH topology
2QADA 4K0AA 4S1RG 3TGRA 3SE9G 4OM0G 1G9MG 4LSTG 4YFLE 4DVSA 3HI1G 5FA2A 2NY6A 4RFOG 5TE7G 4DKUA 4OLZG 3FUSA 5TE6G 5I9QA 3U7YG 4DVTA 3IDXG 3TGSA 2NY0A 4KA2A 4J6RG 4LSVG 4R4FA 5F9WA 4JPVG 1G9NG 5FECC 4DKOA 4DKVA 4LSUG 1RZJG 4S1QG 4XMPG 4XNYG 4XVSG 4DKQA 3SE8G 3IDYA 4DVWA 4I54A 5TE4G 4OLXG 4H8WG 4LAJA 2NY2A 1GC1G 3TGQA 5T33G 2NY4A 4LSRG 4YDKG 3RJQA 4OLVG 4DVVA 5F96G 2NXZA 4RWYA 4DKPA 1RZKG 4XNZA 5F4PA 4OLYG 2I60G 4JZZA 4LSQG 4JPWG 4JZWA 2B4CG 5CD5A 4S1SG 3JWOA 2NY5G 3TIHA 4I53A 2NY1A 4DVRG 4LSPG 5IGXG 2BF1A 4YE4G 4DVXA 5F4LA 4P9HG 4RFNA 3JWDA 4YDIG 2NXYA 5CAYG 4LSSG 4YDLA 4RX4E 4XVTG 3LQAG 4OLUG 4OLWG 1YYMG 1YYLG 2NY3A 5F4RA 4DKRA 4JB9G 3NGBA 5F4UA 4JKPG 4R2GA 5F9OG 2I5YG 4JDTG 2NY7G 4OM1G 4R4NA 3TGTA 4YDJG 4JM2E 4RZ8A 5KJRG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QAD A;  4K0A A;  4S1R G;  3TGR A;  3SE9 G;  4OM0 G;  1G9M G;  4LST G;  4YFL E;  4DVS A;  3HI1 G;  5FA2 A;  2NY6 A;  4RFO G;  5TE7 G;  4DKU A;  4OLZ G;  3FUS A;  5TE6 G;  5I9Q A;  3U7Y G;  4DVT A;  3IDX G;  3TGS A;  2NY0 A;  4KA2 A;  4J6R G;  4LSV G;  4R4F A;  5F9W A;  4JPV G;  1G9N G;  5FEC C;  4DKO A;  4DKV A;  4LSU G;  1RZJ G;  4S1Q G;  4XMP G;  4XNY G;  4XVS G;  4DKQ A;  3SE8 G;  3IDY A;  4DVW A;  4I54 A;  5TE4 G;  4OLX G;  4H8W G;  4LAJ A;  2NY2 A;  1GC1 G;  3TGQ A;  5T33 G;  2NY4 A;  4LSR G;  4YDK G;  3RJQ A;  4OLV G;  4DVV A;  5F96 G;  2NXZ A;  4RWY A;  4DKP A;  1RZK G;  4XNZ A;  5F4P A;  4OLY G;  2I60 G;  4JZZ A;  4LSQ G;  4JPW G;  4JZW A;  2B4C G;  5CD5 A;  4S1S G;  3JWO A;  2NY5 G;  3TIH A;  4I53 A;  2NY1 A;  4DVR G;  4LSP G;  5IGX G;  2BF1 A;  4YE4 G;  4DVX A;  5F4L A;  4P9H G;  4RFN A;  3JWD A;  4YDI G;  2NXY A;  5CAY G;  4LSS G;  4YDL A;  4RX4 E;  4XVT G;  3LQA G;  4OLU G;  4OLW G;  1YYM G;  1YYL G;  2NY3 A;  5F4R A;  4DKR A;  4JB9 G;  3NGB A;  5F4U A;  4JKP G;  4R2G A;  5F9O G;  2I5Y G;  4JDT G;  2NY7 G;  4OM1 G;  4R4N A;  3TGT A;  4YDJ G;  4JM2 E;  4RZ8 A;  5KJR G; 
#chains in the Genus database with same CATH topology
 2QAD A;  4K0A A;  4S1R G;  3TGR A;  3SE9 G;  4OM0 G;  1G9M G;  4LST G;  4YFL E;  4DVS A;  3HI1 G;  5FA2 A;  2NY6 A;  4RFO G;  5TE7 G;  4DKU A;  4OLZ G;  3FUS A;  5TE6 G;  5I9Q A;  3U7Y G;  4DVT A;  3IDX G;  3TGS A;  2NY0 A;  4KA2 A;  4J6R G;  4LSV G;  4R4F A;  5F9W A;  4JPV G;  1G9N G;  5FEC C;  4DKO A;  4DKV A;  4LSU G;  1RZJ G;  4S1Q G;  4XMP G;  4XNY G;  4XVS G;  4DKQ A;  3SE8 G;  3IDY A;  4DVW A;  4I54 A;  5TE4 G;  4OLX G;  4H8W G;  4LAJ A;  2NY2 A;  1GC1 G;  3TGQ A;  5T33 G;  2NY4 A;  4LSR G;  4YDK G;  3RJQ A;  4OLV G;  4DVV A;  5F96 G;  2NXZ A;  4RWY A;  4DKP A;  1RZK G;  4XNZ A;  5F4P A;  4OLY G;  2I60 G;  4JZZ A;  4LSQ G;  4JPW G;  4JZW A;  2B4C G;  5CD5 A;  4S1S G;  3JWO A;  2NY5 G;  3TIH A;  4I53 A;  2NY1 A;  4DVR G;  4LSP G;  5IGX G;  2BF1 A;  4YE4 G;  4DVX A;  5F4L A;  4P9H G;  4RFN A;  3JWD A;  4YDI G;  2NXY A;  5CAY G;  4LSS G;  4YDL A;  4RX4 E;  4XVT G;  3LQA G;  4OLU G;  4OLW G;  1YYM G;  1YYL G;  2NY3 A;  5F4R A;  4DKR A;  4JB9 G;  3NGB A;  5F4U A;  4JKP G;  4R2G A;  5F9O G;  2I5Y G;  4JDT G;  2NY7 G;  4OM1 G;  4R4N A;  3TGT A;  4YDJ G;  4JM2 E;  4RZ8 A;  5KJR G; 
#chains in the Genus database with same CATH homology
 2QAD A;  4K0A A;  4S1R G;  3TGR A;  3SE9 G;  4OM0 G;  1G9M G;  4LST G;  4YFL E;  4DVS A;  3HI1 G;  5FA2 A;  2NY6 A;  4RFO G;  5TE7 G;  4DKU A;  4OLZ G;  3FUS A;  5TE6 G;  5I9Q A;  3U7Y G;  4DVT A;  3IDX G;  3TGS A;  2NY0 A;  4KA2 A;  4J6R G;  4LSV G;  4R4F A;  5F9W A;  4JPV G;  1G9N G;  5FEC C;  4DKO A;  4DKV A;  4LSU G;  1RZJ G;  4S1Q G;  4XMP G;  4XNY G;  4XVS G;  4DKQ A;  3SE8 G;  3IDY A;  4DVW A;  4I54 A;  5TE4 G;  4OLX G;  4H8W G;  4LAJ A;  2NY2 A;  1GC1 G;  3TGQ A;  5T33 G;  2NY4 A;  4LSR G;  4YDK G;  3RJQ A;  4OLV G;  4DVV A;  5F96 G;  2NXZ A;  4RWY A;  4DKP A;  1RZK G;  4XNZ A;  5F4P A;  4OLY G;  2I60 G;  4JZZ A;  4LSQ G;  4JPW G;  4JZW A;  2B4C G;  5CD5 A;  4S1S G;  3JWO A;  2NY5 G;  3TIH A;  4I53 A;  2NY1 A;  4DVR G;  4LSP G;  5IGX G;  2BF1 A;  4YE4 G;  4DVX A;  5F4L A;  4P9H G;  4RFN A;  3JWD A;  4YDI G;  2NXY A;  5CAY G;  4LSS G;  4YDL A;  4RX4 E;  4XVT G;  3LQA G;  4OLU G;  4OLW G;  1YYM G;  1YYL G;  2NY3 A;  5F4R A;  4DKR A;  4JB9 G;  3NGB A;  5F4U A;  4JKP G;  4R2G A;  5F9O G;  2I5Y G;  4JDT G;  2NY7 G;  4OM1 G;  4R4N A;  3TGT A;  4YDJ G;  4JM2 E;  4RZ8 A;  5KJR G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...