5KK2A

Architecture of fully occupied glua2 ampa receptor - tarp complex elucidated by single particle cryo-electron microscopy
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
433
structure length
408
Chain Sequence
TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRSSESTNEFGIFNSLWFSLGAFMRQDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Membrane protein, transport protein, signaling protein
molecule keywords Glutamate receptor 2
publication title Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 120
structure length 408
sequence length 433
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2016-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00060 Lig_chan Ligand-gated ion channel
A PF01094 ANF_receptor Receptor family ligand binding region
A PF10613 Lig_chan-Glu_bd Ligated ion channel L-glutamate- and glycine-binding site
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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