5P2P | Genus

Total Genus 36

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	36
sequence length	119
structure length	119
Chain Sequence	ALFQFRSMIKCAIPGSHPLMDFNNYGCYCGWGGSGTPVDELDRCCETHDNCYRDAKNLSGCYPYTESYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5d0191bb832c0da8dbc843b3/pdb.gz

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loadScript /static/js/j2s/core/corezip.z.js

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5d0191bb832c0da8dbc843b3/pdb.gz): 2281 ms

reading 119 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

119 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 20 ms

Adding embedded #jmolscript: select ({0:118});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase(carboxylic ester)
source organism	Sus scrofa
publication title	X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor. pubmed doi rcsb
molecule keywords	PHOSPHOLIPASE A2
total genus	36
structure length	119
sequence length	119
chains with identical sequence	B
ec nomenclature	ec 3.1.1.4: Phospholipase A(2).
pdb deposition date	1990-09-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00068	Phospholip_A2_1	Phospholipase A2

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.90.10	Mainly Alpha	Up-down Bundle	Phospholipase A2	Phospholipase A2 domain	5p2pA00

2QHEA 1RGBA 2FNXA 1Q7AA 3JTIA 1TG4A 5P2PA 2I0UA 1BP2A 2Q2JA 3VBZA 3T0RA 1LE6A 1G4IA 1MF4A 3ELOA 3JQ5A 2G58A 3P2PA 2PHIA 1PISA 2WQ5A 2GNSA 1TP2A 3VC0A 1OWSA 1CLPA 1TJKA 1FXFA 3DIHA 3NJUA 2B04A 1GMZA 2BAXA 2BPPA 3V9MA 4QF7A 1OXLA 2OQDA 3I3IA 2QOGA 2ARMA 3U8HA 1MH2A 1FV0A 1KVOA 1SKGA 1MC2A 2OSNA 2ZP3A 1C1JA 3BP2A 3CXIA 1KVYA 4GLDA 4QGDA 1JLTA 2QUEA 1BVMA 3R0LD 1OZ6A 1MKTA 1S6BB 1ZLBA 1BPQA 1G0ZA 1OYFA 2B03A 1TG1A 1PIRA 4HG9A 1DB4A 1BJJA 1DB5A 4G5IA 2O1NA 1M8SA 4HMBA 1A3DA 4QERA 4BP2A 4WTBA 2H4CA 3FVIA 2OTHA 1CEHA 2WG8B 1MKUA 4QEMA 1OQSA 1POEA 2PB8A 1Y4LA 1POAA 1PWOA 2PH4A 1OZYA 1TH6A 1A3FA 1KVWA 3O4MA 1OWSB 2WG8A 1LN8A 1PP2L 1KQUA 3U8DA 4YU7A 1IRBA 4EIXA 1C74A 4QMCA 1L8SA 1SV3A 2QOGB 1T37A 1M8RA 2WG9A 1Q5TA 1MH2B 1Y75A 1FE5A 2OUBA 1TD7A 1TDVA 1PC9A 1LE7A 1BBCA 1SXKA 4K06A 1UNEA 2QVDA 4NTYC 2OYFA 2AOZA 5G3NA 1JLTB 4NTXC 1KP4A 3I3HA 2ZP4A 1OYFB 2PVTA 1Y6OA 1UMVX 2OK9A 1S8GA 1POCA 3G8HA 1PSJA 1Q6VA 2B00A 3H1XA 1Z76A 3QNLA 1SQZA 1SFWA 4H0SA 1POBA 2PWSA 1QLLA 3OSHA 1PSHA 1S8HA 1VKQA 2H4CB 3JR8A 2NOTA 3MLMA 2H8IA 1OQSB 3L30A 3FVJA 3FG5A 1MH8A 1J1AA 5G3MA 1TC8A 3HZDA 4O1YA 4YV5A 3GCIA 1CL5A 1AOKB 1LWBA 1YXLA 2PMJA 2DPZA 1TK4A 2BCHA 1MG6A 1U4JA 1PPAA 3IQ3A 3JQLA 1PODA 1PO8A 4UY1A 1IT5A 1S8IA 4KF3A 1ZM6A 1ZYXA 1AOKA 4E4CA 1P2PA 1AYPA 1DCYA 1M8TA 1O2EA 4DBKA 1TJ9A 2DO2A 1Y75B 1KPMA 1KVXA 1XXSA 2BD1A 1N29A 1ZL7A 1B4WA 1MKVA 3G8GA 1ZWPA 2ZBHA 1P7OA 3HSWA 2OLIA 2RD4A 1ZR8A 2B01A 2AZZA 1FB2A 3QLMA 2B96A 2QHWA 2OSHA 4DCFA 3FO7A 1SFVA 3CYLA 4YZ7A 2AZYA 1Y6PA 3BJWA 1PA0A 1IT4A 4RFPA 3Q4YA 1VIPA 3CBIA 3I03A 1FX9A 1MH7A 1GP7A 4GFYA 3U8IA 1JIAA 1BK9A 4QF8A 4K09A 1G2XA 2Q1PA 2OTFA 1SZ8A 1JQ9A 1YXHA 1TGMA 4NTWC 1N28A 1GH4A 1FAZA 2BP2A 4FGAA 1VPIA 1SV9A 3G8FA 2B17A 3UX7A 4AUPA 1U73A 1XXWB 2QU9A 2ZP5A 1OXRA 1BUNA 1A2AA 2PYCA 1GODA 1MKSA 1S6BA 1IJLA 3U8BA 1Y38A 1XXWA 1DPYA 1HN4A 1VAPA 1O3WA 1VL9A 2WG7A 1FDKA 1JQ8A 4P2PA 2QHDA 2RD4B 3HZWA 1AE7A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2QHE A;  1RGB A;  2FNX A;  1Q7A A;  3JTI A;  1TG4 A;  5P2P A;  2I0U A;  1BP2 A;  2Q2J A;  3VBZ A;  3T0R A;  1LE6 A;  1G4I A;  1MF4 A;  3ELO A;  3JQ5 A;  2G58 A;  3P2P A;  2PHI A;  1PIS A;  2WQ5 A;  2GNS A;  1TP2 A;  3VC0 A;  1OWS A;  1CLP A;  1TJK A;  1FXF A;  3DIH A;  3NJU A;  2B04 A;  1GMZ A;  2BAX A;  2BPP A;  3V9M A;  4QF7 A;  1OXL A;  2OQD A;  3I3I A;  2QOG A;  2ARM A;  3U8H A;  1MH2 A;  1FV0 A;  1KVO A;  1SKG A;  1MC2 A;  2OSN A;  2ZP3 A;  1C1J A;  3BP2 A;  3CXI A;  1KVY A;  4GLD A;  4QGD A;  1JLT A;  2QUE A;  1BVM A;  3R0L D;  1OZ6 A;  1MKT A;  1S6B B;  1ZLB A;  1BPQ A;  1G0Z A;  1OYF A;  2B03 A;  1TG1 A;  1PIR A;  4HG9 A;  1DB4 A;  1BJJ A;  1DB5 A;  4G5I A;  2O1N A;  1M8S A;  4HMB A;  1A3D A;  4QER A;  4BP2 A;  4WTB A;  2H4C A;  3FVI A;  2OTH A;  1CEH A;  2WG8 B;  1MKU A;  4QEM A;  1OQS A;  1POE A;  2PB8 A;  1Y4L A;  1POA A;  1PWO A;  2PH4 A;  1OZY A;  1TH6 A;  1A3F A;  1KVW A;  3O4M A;  1OWS B;  2WG8 A;  1LN8 A;  1PP2 L;  1KQU A;  3U8D A;  4YU7 A;  1IRB A;  4EIX A;  1C74 A;  4QMC A;  1L8S A;  1SV3 A;  2QOG B;  1T37 A;  1M8R A;  2WG9 A;  1Q5T A;  1MH2 B;  1Y75 A;  1FE5 A;  2OUB A;  1TD7 A;  1TDV A;  1PC9 A;  1LE7 A;  1BBC A;  1SXK A;  4K06 A;  1UNE A;  2QVD A;  4NTY C;  2OYF A;  2AOZ A;  5G3N A;  1JLT B;  4NTX C;  1KP4 A;  3I3H A;  2ZP4 A;  1OYF B;  2PVT A;  1Y6O A;  1UMV X;  2OK9 A;  1S8G A;  1POC A;  3G8H A;  1PSJ A;  1Q6V A;  2B00 A;  3H1X A;  1Z76 A;  3QNL A;  1SQZ A;  1SFW A;  4H0S A;  1POB A;  2PWS A;  1QLL A;  3OSH A;  1PSH A;  1S8H A;  1VKQ A;  2H4C B;  3JR8 A;  2NOT A;  3MLM A;  2H8I A;  1OQS B;  3L30 A;  3FVJ A;  3FG5 A;  1MH8 A;  1J1A A;  5G3M A;  1TC8 A;  3HZD A;  4O1Y A;  4YV5 A;  3GCI A;  1CL5 A;  1AOK B;  1LWB A;  1YXL A;  2PMJ A;  2DPZ A;  1TK4 A;  2BCH A;  1MG6 A;  1U4J A;  1PPA A;  3IQ3 A;  3JQL A;  1POD A;  1PO8 A;  4UY1 A;  1IT5 A;  1S8I A;  4KF3 A;  1ZM6 A;  1ZYX A;  1AOK A;  4E4C A;  1P2P A;  1AYP A;  1DCY A;  1M8T A;  1O2E A;  4DBK A;  1TJ9 A;  2DO2 A;  1Y75 B;  1KPM A;  1KVX A;  1XXS A;  2BD1 A;  1N29 A;  1ZL7 A;  1B4W A;  1MKV A;  3G8G A;  1ZWP A;  2ZBH A;  1P7O A;  3HSW A;  2OLI A;  2RD4 A;  1ZR8 A;  2B01 A;  2AZZ A;  1FB2 A;  3QLM A;  2B96 A;  2QHW A;  2OSH A;  4DCF A;  3FO7 A;  1SFV A;  3CYL A;  4YZ7 A;  2AZY A;  1Y6P A;  3BJW A;  1PA0 A;  1IT4 A;  4RFP A;  3Q4Y A;  1VIP A;  3CBI A;  3I03 A;  1FX9 A;  1MH7 A;  1GP7 A;  4GFY A;  3U8I A;  1JIA A;  1BK9 A;  4QF8 A;  4K09 A;  1G2X A;  2Q1P A;  2OTF A;  1SZ8 A;  1JQ9 A;  1YXH A;  1TGM A;  4NTW C;  1N28 A;  1GH4 A;  1FAZ A;  2BP2 A;  4FGA A;  1VPI A;  1SV9 A;  3G8F A;  2B17 A;  3UX7 A;  4AUP A;  1U73 A;  1XXW B;  2QU9 A;  2ZP5 A;  1OXR A;  1BUN A;  1A2A A;  2PYC A;  1GOD A;  1MKS A;  1S6B A;  1IJL A;  3U8B A;  1Y38 A;  1XXW A;  1DPY A;  1HN4 A;  1VAP A;  1O3W A;  1VL9 A;  2WG7 A;  1FDK A;  1JQ8 A;  4P2P A;  2QHD A;  2RD4 B;  3HZW A;  1AE7 A; 
#chains in the Genus database with same CATH topology
 2QHE A;  1RGB A;  2FNX A;  1Q7A A;  3JTI A;  1TG4 A;  5P2P A;  2I0U A;  1BP2 A;  2Q2J A;  3VBZ A;  3T0R A;  1LE6 A;  1G4I A;  1MF4 A;  3ELO A;  3JQ5 A;  2G58 A;  3P2P A;  2PHI A;  1PIS A;  2WQ5 A;  2GNS A;  1TP2 A;  3VC0 A;  1OWS A;  1CLP A;  1TJK A;  1FXF A;  3DIH A;  3NJU A;  2B04 A;  1GMZ A;  2BAX A;  2BPP A;  3V9M A;  4QF7 A;  1OXL A;  2OQD A;  3I3I A;  2QOG A;  2ARM A;  3U8H A;  1MH2 A;  1FV0 A;  1KVO A;  1SKG A;  1MC2 A;  2OSN A;  2ZP3 A;  1C1J A;  3BP2 A;  3CXI A;  1KVY A;  4GLD A;  4QGD A;  1JLT A;  2QUE A;  1BVM A;  3R0L D;  1OZ6 A;  1MKT A;  1S6B B;  1ZLB A;  1BPQ A;  1G0Z A;  1OYF A;  2B03 A;  1TG1 A;  1PIR A;  4HG9 A;  1DB4 A;  1BJJ A;  1DB5 A;  4G5I A;  2O1N A;  1M8S A;  4HMB A;  1A3D A;  4QER A;  4BP2 A;  4WTB A;  2H4C A;  3FVI A;  2OTH A;  1CEH A;  2WG8 B;  1MKU A;  4QEM A;  1OQS A;  1POE A;  2PB8 A;  1Y4L A;  1POA A;  1PWO A;  2PH4 A;  1OZY A;  1TH6 A;  1A3F A;  1KVW A;  3O4M A;  1OWS B;  2WG8 A;  1LN8 A;  1PP2 L;  1KQU A;  3U8D A;  4YU7 A;  1IRB A;  4EIX A;  1C74 A;  4QMC A;  1L8S A;  1SV3 A;  2QOG B;  1T37 A;  1M8R A;  2WG9 A;  1Q5T A;  1MH2 B;  1Y75 A;  1FE5 A;  2OUB A;  1TD7 A;  1TDV A;  1PC9 A;  1LE7 A;  1BBC A;  1SXK A;  4K06 A;  1UNE A;  2QVD A;  4NTY C;  2OYF A;  2AOZ A;  5G3N A;  1JLT B;  4NTX C;  1KP4 A;  3I3H A;  2ZP4 A;  1OYF B;  2PVT A;  1Y6O A;  1UMV X;  2OK9 A;  1S8G A;  1POC A;  3G8H A;  1PSJ A;  1Q6V A;  2B00 A;  3H1X A;  1Z76 A;  3QNL A;  1SQZ A;  1SFW A;  4H0S A;  1POB A;  2PWS A;  1QLL A;  3OSH A;  1PSH A;  1S8H A;  1VKQ A;  2H4C B;  3JR8 A;  2NOT A;  3MLM A;  2H8I A;  1OQS B;  3L30 A;  3FVJ A;  3FG5 A;  1MH8 A;  1J1A A;  5G3M A;  1TC8 A;  3HZD A;  4O1Y A;  4YV5 A;  3GCI A;  1CL5 A;  1AOK B;  1LWB A;  1YXL A;  2PMJ A;  2DPZ A;  1TK4 A;  2BCH A;  1MG6 A;  1U4J A;  1PPA A;  3IQ3 A;  3JQL A;  1POD A;  1PO8 A;  4UY1 A;  1IT5 A;  1S8I A;  4KF3 A;  1ZM6 A;  1ZYX A;  1AOK A;  4E4C A;  1P2P A;  1AYP A;  1DCY A;  1M8T A;  1O2E A;  4DBK A;  1TJ9 A;  2DO2 A;  1Y75 B;  1KPM A;  1KVX A;  1XXS A;  2BD1 A;  1N29 A;  1ZL7 A;  1B4W A;  1MKV A;  3G8G A;  1ZWP A;  2ZBH A;  1P7O A;  3HSW A;  2OLI A;  2RD4 A;  1ZR8 A;  2B01 A;  2AZZ A;  1FB2 A;  3QLM A;  2B96 A;  2QHW A;  2OSH A;  4DCF A;  3FO7 A;  1SFV A;  3CYL A;  4YZ7 A;  2AZY A;  1Y6P A;  3BJW A;  1PA0 A;  1IT4 A;  4RFP A;  3Q4Y A;  1VIP A;  3CBI A;  3I03 A;  1FX9 A;  1MH7 A;  1GP7 A;  4GFY A;  3U8I A;  1JIA A;  1BK9 A;  4QF8 A;  4K09 A;  1G2X A;  2Q1P A;  2OTF A;  1SZ8 A;  1JQ9 A;  1YXH A;  1TGM A;  4NTW C;  1N28 A;  1GH4 A;  1FAZ A;  2BP2 A;  4FGA A;  1VPI A;  1SV9 A;  3G8F A;  2B17 A;  3UX7 A;  4AUP A;  1U73 A;  1XXW B;  2QU9 A;  2ZP5 A;  1OXR A;  1BUN A;  1A2A A;  2PYC A;  1GOD A;  1MKS A;  1S6B A;  1IJL A;  3U8B A;  1Y38 A;  1XXW A;  1DPY A;  1HN4 A;  1VAP A;  1O3W A;  1VL9 A;  2WG7 A;  1FDK A;  1JQ8 A;  4P2P A;  2QHD A;  2RD4 B;  3HZW A;  1AE7 A; 
#chains in the Genus database with same CATH homology
 2QHE A;  1RGB A;  2FNX A;  1Q7A A;  3JTI A;  1TG4 A;  5P2P A;  2I0U A;  1BP2 A;  2Q2J A;  3VBZ A;  3T0R A;  1LE6 A;  1G4I A;  1MF4 A;  3ELO A;  3JQ5 A;  2G58 A;  3P2P A;  2PHI A;  1PIS A;  2WQ5 A;  2GNS A;  1TP2 A;  3VC0 A;  1OWS A;  1CLP A;  1TJK A;  1FXF A;  3DIH A;  3NJU A;  2B04 A;  1GMZ A;  2BAX A;  2BPP A;  3V9M A;  4QF7 A;  1OXL A;  2OQD A;  3I3I A;  2QOG A;  2ARM A;  3U8H A;  1MH2 A;  1FV0 A;  1KVO A;  1SKG A;  1MC2 A;  2OSN A;  2ZP3 A;  1C1J A;  3BP2 A;  3CXI A;  1KVY A;  4GLD A;  4QGD A;  1JLT A;  2QUE A;  1BVM A;  3R0L D;  1OZ6 A;  1MKT A;  1S6B B;  1ZLB A;  1BPQ A;  1G0Z A;  1OYF A;  2B03 A;  1TG1 A;  1PIR A;  4HG9 A;  1DB4 A;  1BJJ A;  1DB5 A;  4G5I A;  2O1N A;  1M8S A;  4HMB A;  1A3D A;  4QER A;  4BP2 A;  4WTB A;  2H4C A;  3FVI A;  2OTH A;  1CEH A;  2WG8 B;  1MKU A;  4QEM A;  1OQS A;  1POE A;  2PB8 A;  1Y4L A;  1POA A;  1PWO A;  2PH4 A;  1OZY A;  1TH6 A;  1A3F A;  1KVW A;  3O4M A;  1OWS B;  2WG8 A;  1LN8 A;  1PP2 L;  1KQU A;  3U8D A;  4YU7 A;  1IRB A;  4EIX A;  1C74 A;  4QMC A;  1L8S A;  1SV3 A;  2QOG B;  1T37 A;  1M8R A;  2WG9 A;  1Q5T A;  1MH2 B;  1Y75 A;  1FE5 A;  2OUB A;  1TD7 A;  1TDV A;  1PC9 A;  1LE7 A;  1BBC A;  1SXK A;  4K06 A;  1UNE A;  2QVD A;  4NTY C;  2OYF A;  2AOZ A;  5G3N A;  1JLT B;  4NTX C;  1KP4 A;  3I3H A;  2ZP4 A;  1OYF B;  2PVT A;  1Y6O A;  1UMV X;  2OK9 A;  1S8G A;  1POC A;  3G8H A;  1PSJ A;  1Q6V A;  2B00 A;  3H1X A;  1Z76 A;  3QNL A;  1SQZ A;  1SFW A;  4H0S A;  1POB A;  2PWS A;  1QLL A;  3OSH A;  1PSH A;  1S8H A;  1VKQ A;  2H4C B;  3JR8 A;  2NOT A;  3MLM A;  2H8I A;  1OQS B;  3L30 A;  3FVJ A;  3FG5 A;  1MH8 A;  1J1A A;  5G3M A;  1TC8 A;  3HZD A;  4O1Y A;  4YV5 A;  3GCI A;  1CL5 A;  1AOK B;  1LWB A;  1YXL A;  2PMJ A;  2DPZ A;  1TK4 A;  2BCH A;  1MG6 A;  1U4J A;  1PPA A;  3IQ3 A;  3JQL A;  1POD A;  1PO8 A;  4UY1 A;  1IT5 A;  1S8I A;  4KF3 A;  1ZM6 A;  1ZYX A;  1AOK A;  4E4C A;  1P2P A;  1AYP A;  1DCY A;  1M8T A;  1O2E A;  4DBK A;  1TJ9 A;  2DO2 A;  1Y75 B;  1KPM A;  1KVX A;  1XXS A;  2BD1 A;  1N29 A;  1ZL7 A;  1B4W A;  1MKV A;  3G8G A;  1ZWP A;  2ZBH A;  1P7O A;  3HSW A;  2OLI A;  2RD4 A;  1ZR8 A;  2B01 A;  2AZZ A;  1FB2 A;  3QLM A;  2B96 A;  2QHW A;  2OSH A;  4DCF A;  3FO7 A;  1SFV A;  3CYL A;  4YZ7 A;  2AZY A;  1Y6P A;  3BJW A;  1PA0 A;  1IT4 A;  4RFP A;  3Q4Y A;  1VIP A;  3CBI A;  3I03 A;  1FX9 A;  1MH7 A;  1GP7 A;  4GFY A;  3U8I A;  1JIA A;  1BK9 A;  4QF8 A;  4K09 A;  1G2X A;  2Q1P A;  2OTF A;  1SZ8 A;  1JQ9 A;  1YXH A;  1TGM A;  4NTW C;  1N28 A;  1GH4 A;  1FAZ A;  2BP2 A;  4FGA A;  1VPI A;  1SV9 A;  3G8F A;  2B17 A;  3UX7 A;  4AUP A;  1U73 A;  1XXW B;  2QU9 A;  2ZP5 A;  1OXR A;  1BUN A;  1A2A A;  2PYC A;  1GOD A;  1MKS A;  1S6B A;  1IJL A;  3U8B A;  1Y38 A;  1XXW A;  1DPY A;  1HN4 A;  1VAP A;  1O3W A;  1VL9 A;  2WG7 A;  1FDK A;  1JQ8 A;  4P2P A;  2QHD A;  2RD4 B;  3HZW A;  1AE7 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5P2PA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations