5TE6G

Crystal structure of broadly neutralizing vrc01-class antibody n6 in complex with hiv-1 clade ae strain 93th057 gp120 core
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
353
structure length
341
Chain Sequence
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEFFYCNTTQLFNNTCIGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
pubmed doi rcsb
molecule tags Immune system
source organism Human immunodeficiency virus 1
molecule keywords clade A/E 93TH057 HIV-1 gp120 core
total genus 83
structure length 341
sequence length 353
ec nomenclature
pdb deposition date 2016-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00516 GP120 Envelope glycoprotein GP120
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 5te6G01
3TIHA 4XVTG 3IDYA 2NY2A 3SE8G 4LSRG 4OLWG 2NXZA 4DKQA 4OLXG 4YDJG 4XNYG 3RJQA 4DKUA 5F4PA 4J6RG 4DVSA 3TGTA 5F4RA 4I54A 5IGXG 4JB9G 4JDTG 4JPWG 4LSUG 3TGSA 2NY4A 3JWOA 4K0AA 4DKRA 4RFNA 1G9NG 4OLZG 2NY3A 3TGRA 4DVXA 1GC1G 5F9OG 4JZWA 4LSQG 3NGBA 4P9HG 4RX4E 4LSSG 4DVTA 4LSTG 4OM0G 4RZ8A 4XMPG 4DKPA 4YDIG 4OLYG 5F96G 4YFLE 2NY1A 4S1RG 5FECC 4JZZA 4S1QG 4XVSG 3U7YG 3HI1G 3IDXG 4LSVG 4DKVA 2NY5G 5F4LA 2B4CG 4JKPG 4YE4G 4LSPG 3SE9G 5F9WA 2BF1A 4DVRG 1G9MG 4OM1G 4OLUG 4DKOA 4R2GA 4OLVG 4KA2A 2NY7G 5T33G 4XNZA 5KJRG 2QADA 4H8WG 5F4UA 4R4FA 2I60G 2NY0A 4JM2E 1YYMG 4DVVA 4RFOG 4YDKG 4R4NA 5I9QA 3TGQA 4YDLA 5CAYG 1RZKG 4DVWA 5TE7G 5CD5A 4S1SG 4I53A 3LQAG 5TE4G 2NY6A 2I5YG 1RZJG 2NXYA 4RWYA 3JWDA 1YYLG 3FUSA 5TE6G 5FA2A 4LAJA 4JPVG
chains in the Genus database with same CATH superfamily
3TIHA 4XVTG 3IDYA 2NY2A 3SE8G 4LSRG 4OLWG 2NXZA 4DKQA 4OLXG 4YDJG 4XNYG 3RJQA 4DKUA 5F4PA 4J6RG 4DVSA 3TGTA 5F4RA 4I54A 5IGXG 4JB9G 4JDTG 4JPWG 4LSUG 3TGSA 2NY4A 3JWOA 4K0AA 4DKRA 4RFNA 1G9NG 4OLZG 2NY3A 3TGRA 4DVXA 1GC1G 5F9OG 4JZWA 4LSQG 3NGBA 4P9HG 4RX4E 4LSSG 4DVTA 4LSTG 4OM0G 4RZ8A 4XMPG 4DKPA 4YDIG 4OLYG 5F96G 4YFLE 2NY1A 4S1RG 5FECC 4JZZA 4S1QG 4XVSG 3U7YG 3HI1G 3IDXG 4LSVG 4DKVA 2NY5G 5F4LA 2B4CG 4JKPG 4YE4G 4LSPG 3SE9G 5F9WA 2BF1A 4DVRG 1G9MG 4OM1G 4OLUG 4DKOA 4R2GA 4OLVG 4KA2A 2NY7G 5T33G 4XNZA 5KJRG 2QADA 4H8WG 5F4UA 4R4FA 2I60G 2NY0A 4JM2E 1YYMG 4DVVA 4RFOG 4YDKG 4R4NA 5I9QA 3TGQA 4YDLA 5CAYG 1RZKG 4DVWA 5TE7G 5CD5A 4S1SG 4I53A 3LQAG 5TE4G 2NY6A 2I5YG 1RZJG 2NXYA 4RWYA 3JWDA 1YYLG 3FUSA 5TE6G 5FA2A 4LAJA 4JPVG
chains in the Genus database with same CATH topology
3TIHA 4XVTG 3IDYA 2NY2A 3SE8G 4LSRG 4OLWG 2NXZA 4DKQA 4OLXG 4YDJG 4XNYG 3RJQA 4DKUA 5F4PA 4J6RG 4DVSA 3TGTA 5F4RA 4I54A 5IGXG 4JB9G 4JDTG 4JPWG 4LSUG 3TGSA 2NY4A 3JWOA 4K0AA 4DKRA 4RFNA 1G9NG 4OLZG 2NY3A 3TGRA 4DVXA 1GC1G 5F9OG 4JZWA 4LSQG 3NGBA 4P9HG 4RX4E 4LSSG 4DVTA 4LSTG 4OM0G 4RZ8A 4XMPG 4DKPA 4YDIG 4OLYG 5F96G 4YFLE 2NY1A 4S1RG 5FECC 4JZZA 4S1QG 4XVSG 3U7YG 3HI1G 3IDXG 4LSVG 4DKVA 2NY5G 5F4LA 2B4CG 4JKPG 4YE4G 4LSPG 3SE9G 5F9WA 2BF1A 4DVRG 1G9MG 4OM1G 4OLUG 4DKOA 4R2GA 4OLVG 4KA2A 2NY7G 5T33G 4XNZA 5KJRG 2QADA 4H8WG 5F4UA 4R4FA 2I60G 2NY0A 4JM2E 1YYMG 4DVVA 4RFOG 4YDKG 4R4NA 5I9QA 3TGQA 4YDLA 5CAYG 1RZKG 4DVWA 5TE7G 5CD5A 4S1SG 4I53A 3LQAG 5TE4G 2NY6A 2I5YG 1RZJG 2NXYA 4RWYA 3JWDA 1YYLG 3FUSA 5TE6G 5FA2A 4LAJA 4JPVG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TIH A;  4XVT G;  3IDY A;  2NY2 A;  3SE8 G;  4LSR G;  4OLW G;  2NXZ A;  4DKQ A;  4OLX G;  4YDJ G;  4XNY G;  3RJQ A;  4DKU A;  5F4P A;  4J6R G;  4DVS A;  3TGT A;  5F4R A;  4I54 A;  5IGX G;  4JB9 G;  4JDT G;  4JPW G;  4LSU G;  3TGS A;  2NY4 A;  3JWO A;  4K0A A;  4DKR A;  4RFN A;  1G9N G;  4OLZ G;  2NY3 A;  3TGR A;  4DVX A;  1GC1 G;  5F9O G;  4JZW A;  4LSQ G;  3NGB A;  4P9H G;  4RX4 E;  4LSS G;  4DVT A;  4LST G;  4OM0 G;  4RZ8 A;  4XMP G;  4DKP A;  4YDI G;  4OLY G;  5F96 G;  4YFL E;  2NY1 A;  4S1R G;  5FEC C;  4JZZ A;  4S1Q G;  4XVS G;  3U7Y G;  3HI1 G;  3IDX G;  4LSV G;  4DKV A;  2NY5 G;  5F4L A;  2B4C G;  4JKP G;  4YE4 G;  4LSP G;  3SE9 G;  5F9W A;  2BF1 A;  4DVR G;  1G9M G;  4OM1 G;  4OLU G;  4DKO A;  4R2G A;  4OLV G;  4KA2 A;  2NY7 G;  5T33 G;  4XNZ A;  5KJR G;  2QAD A;  4H8W G;  5F4U A;  4R4F A;  2I60 G;  2NY0 A;  4JM2 E;  1YYM G;  4DVV A;  4RFO G;  4YDK G;  4R4N A;  5I9Q A;  3TGQ A;  4YDL A;  5CAY G;  1RZK G;  4DVW A;  5TE7 G;  5CD5 A;  4S1S G;  4I53 A;  3LQA G;  5TE4 G;  2NY6 A;  2I5Y G;  1RZJ G;  2NXY A;  4RWY A;  3JWD A;  1YYL G;  3FUS A;  5TE6 G;  5FA2 A;  4LAJ A;  4JPV G; 
#chains in the Genus database with same CATH topology
 3TIH A;  4XVT G;  3IDY A;  2NY2 A;  3SE8 G;  4LSR G;  4OLW G;  2NXZ A;  4DKQ A;  4OLX G;  4YDJ G;  4XNY G;  3RJQ A;  4DKU A;  5F4P A;  4J6R G;  4DVS A;  3TGT A;  5F4R A;  4I54 A;  5IGX G;  4JB9 G;  4JDT G;  4JPW G;  4LSU G;  3TGS A;  2NY4 A;  3JWO A;  4K0A A;  4DKR A;  4RFN A;  1G9N G;  4OLZ G;  2NY3 A;  3TGR A;  4DVX A;  1GC1 G;  5F9O G;  4JZW A;  4LSQ G;  3NGB A;  4P9H G;  4RX4 E;  4LSS G;  4DVT A;  4LST G;  4OM0 G;  4RZ8 A;  4XMP G;  4DKP A;  4YDI G;  4OLY G;  5F96 G;  4YFL E;  2NY1 A;  4S1R G;  5FEC C;  4JZZ A;  4S1Q G;  4XVS G;  3U7Y G;  3HI1 G;  3IDX G;  4LSV G;  4DKV A;  2NY5 G;  5F4L A;  2B4C G;  4JKP G;  4YE4 G;  4LSP G;  3SE9 G;  5F9W A;  2BF1 A;  4DVR G;  1G9M G;  4OM1 G;  4OLU G;  4DKO A;  4R2G A;  4OLV G;  4KA2 A;  2NY7 G;  5T33 G;  4XNZ A;  5KJR G;  2QAD A;  4H8W G;  5F4U A;  4R4F A;  2I60 G;  2NY0 A;  4JM2 E;  1YYM G;  4DVV A;  4RFO G;  4YDK G;  4R4N A;  5I9Q A;  3TGQ A;  4YDL A;  5CAY G;  1RZK G;  4DVW A;  5TE7 G;  5CD5 A;  4S1S G;  4I53 A;  3LQA G;  5TE4 G;  2NY6 A;  2I5Y G;  1RZJ G;  2NXY A;  4RWY A;  3JWD A;  1YYL G;  3FUS A;  5TE6 G;  5FA2 A;  4LAJ A;  4JPV G; 
#chains in the Genus database with same CATH homology
 3TIH A;  4XVT G;  3IDY A;  2NY2 A;  3SE8 G;  4LSR G;  4OLW G;  2NXZ A;  4DKQ A;  4OLX G;  4YDJ G;  4XNY G;  3RJQ A;  4DKU A;  5F4P A;  4J6R G;  4DVS A;  3TGT A;  5F4R A;  4I54 A;  5IGX G;  4JB9 G;  4JDT G;  4JPW G;  4LSU G;  3TGS A;  2NY4 A;  3JWO A;  4K0A A;  4DKR A;  4RFN A;  1G9N G;  4OLZ G;  2NY3 A;  3TGR A;  4DVX A;  1GC1 G;  5F9O G;  4JZW A;  4LSQ G;  3NGB A;  4P9H G;  4RX4 E;  4LSS G;  4DVT A;  4LST G;  4OM0 G;  4RZ8 A;  4XMP G;  4DKP A;  4YDI G;  4OLY G;  5F96 G;  4YFL E;  2NY1 A;  4S1R G;  5FEC C;  4JZZ A;  4S1Q G;  4XVS G;  3U7Y G;  3HI1 G;  3IDX G;  4LSV G;  4DKV A;  2NY5 G;  5F4L A;  2B4C G;  4JKP G;  4YE4 G;  4LSP G;  3SE9 G;  5F9W A;  2BF1 A;  4DVR G;  1G9M G;  4OM1 G;  4OLU G;  4DKO A;  4R2G A;  4OLV G;  4KA2 A;  2NY7 G;  5T33 G;  4XNZ A;  5KJR G;  2QAD A;  4H8W G;  5F4U A;  4R4F A;  2I60 G;  2NY0 A;  4JM2 E;  1YYM G;  4DVV A;  4RFO G;  4YDK G;  4R4N A;  5I9Q A;  3TGQ A;  4YDL A;  5CAY G;  1RZK G;  4DVW A;  5TE7 G;  5CD5 A;  4S1S G;  4I53 A;  3LQA G;  5TE4 G;  2NY6 A;  2I5Y G;  1RZJ G;  2NXY A;  4RWY A;  3JWD A;  1YYL G;  3FUS A;  5TE6 G;  5FA2 A;  4LAJ A;  4JPV G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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