5TE7G

Crystal structure of broadly neutralizing vrc01-class antibody n6 in complex with hiv-1 clade c strain du172.17 gp120 core
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
348
structure length
336
Chain Sequence
WKEAKTTLFCASDAKAHKEEVHNIWATHACVPTDPNPQEIVLKNVTENFNMWKNDMVDQMHEDIISLWDQSLKPCVKLTGGSAVTQACPKVSFDPIPIHYCAPAGYAILKCNNKTFNGTGPCNNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRFENLTNNAKIIIVHLNESVEINCTRPSNDIRQAHCNISRKKWNTTLQRVKEKLKEKFPNKTIQFAPSSGGDLEITTHSFNCRGEFFYCYTSDLFNSTYMGGANITLQCRIKQIIRMWQGVGQAMYAPPIAGNITCKSNITGLLLTRDGGKKNDTETFRPGGGDMRDNWRSELYKYKVVEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Heavy chain of N6
total genus 81
structure length 336
sequence length 348
ec nomenclature
pdb deposition date 2016-09-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 5te7G01
2B4CG 5FECC 3SE9G 3TGSA 4LSSG 4OLUG 4OM0G 2NY3A 2NY0A 4DKQA 3TGTA 3TIHA 5TE7G 4DVXA 2NY1A 4H8WG 3IDXG 5TE6G 2NY7G 2I60G 4KA2A 4OLWG 4I53A 1RZJG 3NGBA 4RFOG 3RJQA 5I9QA 3IDYA 4DVWA 2NXZA 4JPVG 2QADA 4YDLA 4JDTG 5F9WA 4OM1G 3TGQA 5F9OG 3U7YG 4JB9G 5TE4G 1GC1G 3JWDA 4DKPA 2NY4A 4S1SG 5IGXG 4JM2E 4YFLE 4S1RG 4JPWG 4LSVG 4YDIG 3SE8G 2I5YG 2NY6A 1G9NG 4R4FA 4OLZG 5KJRG 4RFNA 4DVVA 4YE4G 4LSQG 4DKOA 4DKUA 3TGRA 4XNZA 4DVRG 1YYLG 4I54A 4OLYG 4DVSA 1RZKG 2NY2A 1G9MG 4RWYA 3JWOA 4LSTG 2BF1A 4LSRG 5F96G 4LSPG 3HI1G 3LQAG 4DVTA 4XMPG 5F4RA 5CD5A 4K0AA 4JZZA 4RX4E 5T33G 2NXYA 1YYMG 5F4LA 4XVTG 4R2GA 4XVSG 4LSUG 4J6RG 4OLVG 4P9HG 4DKRA 4XNYG 5FA2A 2NY5G 5F4PA 4R4NA 4YDKG 4RZ8A 4JZWA 4OLXG 4YDJG 4S1QG 4DKVA 3FUSA 4LAJA 5F4UA 5CAYG 4JKPG
chains in the Genus database with same CATH superfamily
2B4CG 5FECC 3SE9G 3TGSA 4LSSG 4OLUG 4OM0G 2NY3A 2NY0A 4DKQA 3TGTA 3TIHA 5TE7G 4DVXA 2NY1A 4H8WG 3IDXG 5TE6G 2NY7G 2I60G 4KA2A 4OLWG 4I53A 1RZJG 3NGBA 4RFOG 3RJQA 5I9QA 3IDYA 4DVWA 2NXZA 4JPVG 2QADA 4YDLA 4JDTG 5F9WA 4OM1G 3TGQA 5F9OG 3U7YG 4JB9G 5TE4G 1GC1G 3JWDA 4DKPA 2NY4A 4S1SG 5IGXG 4JM2E 4YFLE 4S1RG 4JPWG 4LSVG 4YDIG 3SE8G 2I5YG 2NY6A 1G9NG 4R4FA 4OLZG 5KJRG 4RFNA 4DVVA 4YE4G 4LSQG 4DKOA 4DKUA 3TGRA 4XNZA 4DVRG 1YYLG 4I54A 4OLYG 4DVSA 1RZKG 2NY2A 1G9MG 4RWYA 3JWOA 4LSTG 2BF1A 4LSRG 5F96G 4LSPG 3HI1G 3LQAG 4DVTA 4XMPG 5F4RA 5CD5A 4K0AA 4JZZA 4RX4E 5T33G 2NXYA 1YYMG 5F4LA 4XVTG 4R2GA 4XVSG 4LSUG 4J6RG 4OLVG 4P9HG 4DKRA 4XNYG 5FA2A 2NY5G 5F4PA 4R4NA 4YDKG 4RZ8A 4JZWA 4OLXG 4YDJG 4S1QG 4DKVA 3FUSA 4LAJA 5F4UA 5CAYG 4JKPG
chains in the Genus database with same CATH topology
2B4CG 5FECC 3SE9G 3TGSA 4LSSG 4OLUG 4OM0G 2NY3A 2NY0A 4DKQA 3TGTA 3TIHA 5TE7G 4DVXA 2NY1A 4H8WG 3IDXG 5TE6G 2NY7G 2I60G 4KA2A 4OLWG 4I53A 1RZJG 3NGBA 4RFOG 3RJQA 5I9QA 3IDYA 4DVWA 2NXZA 4JPVG 2QADA 4YDLA 4JDTG 5F9WA 4OM1G 3TGQA 5F9OG 3U7YG 4JB9G 5TE4G 1GC1G 3JWDA 4DKPA 2NY4A 4S1SG 5IGXG 4JM2E 4YFLE 4S1RG 4JPWG 4LSVG 4YDIG 3SE8G 2I5YG 2NY6A 1G9NG 4R4FA 4OLZG 5KJRG 4RFNA 4DVVA 4YE4G 4LSQG 4DKOA 4DKUA 3TGRA 4XNZA 4DVRG 1YYLG 4I54A 4OLYG 4DVSA 1RZKG 2NY2A 1G9MG 4RWYA 3JWOA 4LSTG 2BF1A 4LSRG 5F96G 4LSPG 3HI1G 3LQAG 4DVTA 4XMPG 5F4RA 5CD5A 4K0AA 4JZZA 4RX4E 5T33G 2NXYA 1YYMG 5F4LA 4XVTG 4R2GA 4XVSG 4LSUG 4J6RG 4OLVG 4P9HG 4DKRA 4XNYG 5FA2A 2NY5G 5F4PA 4R4NA 4YDKG 4RZ8A 4JZWA 4OLXG 4YDJG 4S1QG 4DKVA 3FUSA 4LAJA 5F4UA 5CAYG 4JKPG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B4C G;  5FEC C;  3SE9 G;  3TGS A;  4LSS G;  4OLU G;  4OM0 G;  2NY3 A;  2NY0 A;  4DKQ A;  3TGT A;  3TIH A;  5TE7 G;  4DVX A;  2NY1 A;  4H8W G;  3IDX G;  5TE6 G;  2NY7 G;  2I60 G;  4KA2 A;  4OLW G;  4I53 A;  1RZJ G;  3NGB A;  4RFO G;  3RJQ A;  5I9Q A;  3IDY A;  4DVW A;  2NXZ A;  4JPV G;  2QAD A;  4YDL A;  4JDT G;  5F9W A;  4OM1 G;  3TGQ A;  5F9O G;  3U7Y G;  4JB9 G;  5TE4 G;  1GC1 G;  3JWD A;  4DKP A;  2NY4 A;  4S1S G;  5IGX G;  4JM2 E;  4YFL E;  4S1R G;  4JPW G;  4LSV G;  4YDI G;  3SE8 G;  2I5Y G;  2NY6 A;  1G9N G;  4R4F A;  4OLZ G;  5KJR G;  4RFN A;  4DVV A;  4YE4 G;  4LSQ G;  4DKO A;  4DKU A;  3TGR A;  4XNZ A;  4DVR G;  1YYL G;  4I54 A;  4OLY G;  4DVS A;  1RZK G;  2NY2 A;  1G9M G;  4RWY A;  3JWO A;  4LST G;  2BF1 A;  4LSR G;  5F96 G;  4LSP G;  3HI1 G;  3LQA G;  4DVT A;  4XMP G;  5F4R A;  5CD5 A;  4K0A A;  4JZZ A;  4RX4 E;  5T33 G;  2NXY A;  1YYM G;  5F4L A;  4XVT G;  4R2G A;  4XVS G;  4LSU G;  4J6R G;  4OLV G;  4P9H G;  4DKR A;  4XNY G;  5FA2 A;  2NY5 G;  5F4P A;  4R4N A;  4YDK G;  4RZ8 A;  4JZW A;  4OLX G;  4YDJ G;  4S1Q G;  4DKV A;  3FUS A;  4LAJ A;  5F4U A;  5CAY G;  4JKP G; 
#chains in the Genus database with same CATH topology
 2B4C G;  5FEC C;  3SE9 G;  3TGS A;  4LSS G;  4OLU G;  4OM0 G;  2NY3 A;  2NY0 A;  4DKQ A;  3TGT A;  3TIH A;  5TE7 G;  4DVX A;  2NY1 A;  4H8W G;  3IDX G;  5TE6 G;  2NY7 G;  2I60 G;  4KA2 A;  4OLW G;  4I53 A;  1RZJ G;  3NGB A;  4RFO G;  3RJQ A;  5I9Q A;  3IDY A;  4DVW A;  2NXZ A;  4JPV G;  2QAD A;  4YDL A;  4JDT G;  5F9W A;  4OM1 G;  3TGQ A;  5F9O G;  3U7Y G;  4JB9 G;  5TE4 G;  1GC1 G;  3JWD A;  4DKP A;  2NY4 A;  4S1S G;  5IGX G;  4JM2 E;  4YFL E;  4S1R G;  4JPW G;  4LSV G;  4YDI G;  3SE8 G;  2I5Y G;  2NY6 A;  1G9N G;  4R4F A;  4OLZ G;  5KJR G;  4RFN A;  4DVV A;  4YE4 G;  4LSQ G;  4DKO A;  4DKU A;  3TGR A;  4XNZ A;  4DVR G;  1YYL G;  4I54 A;  4OLY G;  4DVS A;  1RZK G;  2NY2 A;  1G9M G;  4RWY A;  3JWO A;  4LST G;  2BF1 A;  4LSR G;  5F96 G;  4LSP G;  3HI1 G;  3LQA G;  4DVT A;  4XMP G;  5F4R A;  5CD5 A;  4K0A A;  4JZZ A;  4RX4 E;  5T33 G;  2NXY A;  1YYM G;  5F4L A;  4XVT G;  4R2G A;  4XVS G;  4LSU G;  4J6R G;  4OLV G;  4P9H G;  4DKR A;  4XNY G;  5FA2 A;  2NY5 G;  5F4P A;  4R4N A;  4YDK G;  4RZ8 A;  4JZW A;  4OLX G;  4YDJ G;  4S1Q G;  4DKV A;  3FUS A;  4LAJ A;  5F4U A;  5CAY G;  4JKP G; 
#chains in the Genus database with same CATH homology
 2B4C G;  5FEC C;  3SE9 G;  3TGS A;  4LSS G;  4OLU G;  4OM0 G;  2NY3 A;  2NY0 A;  4DKQ A;  3TGT A;  3TIH A;  5TE7 G;  4DVX A;  2NY1 A;  4H8W G;  3IDX G;  5TE6 G;  2NY7 G;  2I60 G;  4KA2 A;  4OLW G;  4I53 A;  1RZJ G;  3NGB A;  4RFO G;  3RJQ A;  5I9Q A;  3IDY A;  4DVW A;  2NXZ A;  4JPV G;  2QAD A;  4YDL A;  4JDT G;  5F9W A;  4OM1 G;  3TGQ A;  5F9O G;  3U7Y G;  4JB9 G;  5TE4 G;  1GC1 G;  3JWD A;  4DKP A;  2NY4 A;  4S1S G;  5IGX G;  4JM2 E;  4YFL E;  4S1R G;  4JPW G;  4LSV G;  4YDI G;  3SE8 G;  2I5Y G;  2NY6 A;  1G9N G;  4R4F A;  4OLZ G;  5KJR G;  4RFN A;  4DVV A;  4YE4 G;  4LSQ G;  4DKO A;  4DKU A;  3TGR A;  4XNZ A;  4DVR G;  1YYL G;  4I54 A;  4OLY G;  4DVS A;  1RZK G;  2NY2 A;  1G9M G;  4RWY A;  3JWO A;  4LST G;  2BF1 A;  4LSR G;  5F96 G;  4LSP G;  3HI1 G;  3LQA G;  4DVT A;  4XMP G;  5F4R A;  5CD5 A;  4K0A A;  4JZZ A;  4RX4 E;  5T33 G;  2NXY A;  1YYM G;  5F4L A;  4XVT G;  4R2G A;  4XVS G;  4LSU G;  4J6R G;  4OLV G;  4P9H G;  4DKR A;  4XNY G;  5FA2 A;  2NY5 G;  5F4P A;  4R4N A;  4YDK G;  4RZ8 A;  4JZW A;  4OLX G;  4YDJ G;  4S1Q G;  4DKV A;  3FUS A;  4LAJ A;  5F4U A;  5CAY G;  4JKP G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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