5TG1A

1.40 a resolution structure of norovirus 3cl protease in complex with the a m-chlorophenyl substituted macrocyclic inhibitor (17-mer)
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
169
structure length
166
Chain Sequence
TLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHGQSGMLLANAKGMDLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSNTVVCAVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease.
pubmed doi rcsb
molecule tags Protease/protease inhibitor
source organism Norwalk virus
molecule keywords 3C-LIKE PROTEASE
total genus 38
structure length 166
sequence length 169
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2016-09-27
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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