5USFA

Leishmania donovani tyrosyl-trna synthetase in complex with nanobody and inhibitor
Total Genus 240
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
240
sequence length
682
structure length
682
Chain Sequence
GSMNTDERYKLLRSVGEECIQESELRNLIEKKPLIRCYDGFEPSGRMHIAQGIFKAVNVNKCTAAGCEFVFWVADWFALMNDKVGGELEKIRIVGRYLIEVWKAAGMDTDKVLFLWSSEEITSHADTYWRMVLDIGRQNTIARIKKCCTIMGKTEGTLTAAQVLYPLMQCCDIFFLKADICQLGLDQRKVNMLAREYCDLIGRKLKPVILSHHMLAGLRRGQAKMSKSDPDSAIFMEDTEEDVARKIRQAYCPRVKQSASAITDDGAPVATDDRNPVLDYFQCVVYARPGAVAAIDGTTYATYEDLEQAFVSDEVSEDALKSCLIDEVNALLAPVRQHFASNEEAHELLEAVKSYRKGGATLPLAETALPAAPEKPHACMWMPALLKVPLDVAEGMIKATEDFIAAHPGGTVTVVLPDWSAVASDEITGVEKDISAALQVNCALLKAYGLPNSVKIVTENEVILGNRNDFWVSVIGIARKNLLSHIEELYGGELRNAGQVIAALMRVATALMLSVSHVISTSLDGHINAFAREYTKERIECVQTLEGRIPALHRPGAAPAVLGADDVLYLDDNDMDIRRKIKKAYSAPNEEANPVISVAQHLLAQHGALNIERGEANGGNVSYNTPEALVADCGSGALHPADLKAAVLQLLLDRSAQARALLNGELKKNMTALRNAEKKMAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.
pubmed doi rcsb
molecule tags Ligase/ligase inhibitor
source organism Leishmania donovani (strain bpk282a1)
molecule keywords Tyrosyl-tRNA synthetase, putative
total genus 240
structure length 682
sequence length 682
chains with identical sequence B
ec nomenclature
pdb deposition date 2017-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00579 tRNA-synt_1b tRNA synthetases class I (W and Y)
Image from the rcsb pdb (www.rcsb.org)
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