5VJQA

Complex between hyhel10 fab fragment heavy chain mutant (i29f, s52t, y53f) and pekin duck egg lysozyme isoform i (del-i)
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
213
structure length
208
Chain Sequence
DVQLQESGPSLVKPSQTLSLTCSVTGDSFTSDYWSWIRKFPGNRLEYMGYVTFSGSTYYNPSLKSRISITRDTSKNQYYLDLNSVTTEDTATYYCANWDGDYWGQGTLVTVSAAKTTPPSVYPLAPGNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
pubmed doi rcsb
molecule tags Hydrolase/immune system
source organism Mus musculus
molecule keywords HyHEL10 heavy chain Fab fragment carrying three mutations; I
total genus 45
structure length 208
sequence length 213
chains with identical sequence C, E, G
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2017-04-19
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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