5W7YA

Crystal structure of fha domain of human aplf in complex with xrcc1 monophosphorylated mutated peptide
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
103
structure length
103
Chain Sequence
GGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILSIPS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Aprataxin and PNK-like factor
total genus 18
structure length 103
sequence length 103
chains with identical sequence B
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2017-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF17913 FHA_2 FHA domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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