5WHEA

Kras g12v/d38p, bound to gppnhp and miniprotein 225-11
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
165
structure length
163
Chain Sequence
TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPEPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exceptionally high-affinity Ras binders that remodel its effector domain.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords GTPase KRas
total genus 63
structure length 163
sequence length 165
chains with identical sequence D, G, J
ec nomenclature
pdb deposition date 2017-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00071 Ras Ras family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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