5WNJA

Crystal structure of murine receptor-interacting protein kinase 4 (ripk4) d143n in complex with lestaurtinib
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
280
structure length
264
Chain Sequence
ALGLLRTFDAGEFAGWEKVGSFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLNLKPANILLDAHYHVKISDFGLAKCFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDLCEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Mus musculus
molecule keywords Receptor-interacting serine/threonine-protein kinase 4
total genus 77
structure length 264
sequence length 280
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2017-08-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00069 Pkinase Protein kinase domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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