5Z56M

Cryo-em structure of a human activated spliceosome (mature bact) at 5.1 angstrom.
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
36
structure length
36
Chain Sequence
ATVRWDYQPDICKDYKETGFCGFGDSCKFLHDRSDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the human activated spliceosome in three conformational states.
pubmed doi rcsb
molecule tags Splicing
molecule keywords Pre-mRNA-processing-splicing factor 8
total genus 3
structure length 36
sequence length 36
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2018-01-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00642 zf-CCCH Zinc finger C-x8-C-x5-C-x3-H type (and similar)
M PF13920 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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