5ZBZA

Crystal structure of the dead domain of human eif4a with sanguinarine
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
216
structure length
204
Chain Sequence
GVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEPSAIQQRAILPCIGYDVIAQAQSGTGTATFAISILQQIELDLATQALVLAPTRELAQQIQVVMALGDYMGASCHACIGGTNVRAEVQLQMEAPHIIVGTPGRVFDMLNRRYLSPYIMFVLDEADEMLSRGFDQIYDIFQLNSNTQVVLLSATMPSDVLEVTFMRDPIRILV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the DEAD domain of Human eIF4A with sanguinarine
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Eukaryotic initiation factor 4A-I
total genus 63
structure length 204
sequence length 216
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2018-02-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00270 DEAD DEAD/DEAH box helicase
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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