5ZWMu

Cryo-em structure of the yeast pre-b complex at an average resolution of 3.4~4.6 angstrom (tri-snrnp and u2 snrnp part)
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
527
structure length
461
Chain Sequence
NLLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFPDTKLPRSSLIAENKIYKFKKVKRKRKQIILQQHEINIFLRDYQEKQQTFNKINFERKLQQLEKELKNEDENFELDINSKKDKYALFSSSSDPSRRTNILSDRARDLDLNEIFTRDEQYGEYMELEQFHSLWLNVIKRGDCSLLQFLDILELFLDDEKYLLTPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAVENLIKSDFEHSYCRGSLRSEAKGIYCPFCSRWFKTSSVFESHLVGKIHKKNESKRRNFVYSEYKLHRYLKYLNDEFSRTRSFVERKLAFTANERMAEMDILTQKYEAPAYDSTEKEGAEQVDMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFNEERHIYHLRCLGIEPSSVFKGITKIKEAQELWKNMQELELEEEDEEGNVMSKKVYDELKKQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
pubmed doi rcsb
molecule tags Splicing
molecule keywords Pre-mRNA-splicing factor 8
total genus 143
structure length 461
sequence length 527
ec nomenclature
pdb deposition date 2018-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
u PF11931 DUF3449 Domain of unknown function (DUF3449)
u PF12171 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding
u PF16837 SF3A3 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
u PF16958 PRP9_N Pre-mRNA-splicing factor PRP9 N-terminus
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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