6X7VA

Crystal structure of the human nudix hydrolase nudt16
Total Genus 42
204060801001201400510152025303540
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
161
structure length
157
Chain Sequence
RHACHALLYAPDPGMLFGRIPLRYAILMQMRFDGRLGFPGGFVDTQDRSLEDGLNRELREELGEAAAAFRVERTDYRSSHVRVVAHFYAKRLTLEELLAVEAGATRAKDHGLEVLGLVRVPLYTLRDGVGGLPTFLENSFIGSAREQLLEALQDLGL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS3 (39-40)3H3 (92-94)3H1 (36-37)S1 (21-30)S6 (59-62)S8 (107-114)S4 (43-50)S5 (54-56)AH1 (69-81)TIV1 (63-66)TVIII1 (64-67)TIV2 (66-69)S7 (95-99)AH2 (117-128)TIV3 (100-107)TII1 (132-135)TI2 (130-133)TIV4 (133-136)AH3 (155-159)TI3 (148-151)S9 (137-143)TI1 (50-53)TIV6 (150-153)S2 (34-35)3H2 (83-87)Updating...
connected with : NaN
publication title Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.
pubmed doi rcsb
molecule keywords U8 snoRNA-decapping enzyme
molecule tags Hydrolase, rna binding protein
source organism Homo sapiens
total genus 42
structure length 157
sequence length 161
chains with identical sequence B, C, D
ec nomenclature ec 3.6.1.62: 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase.
pdb deposition date 2020-05-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00293 NUDIX NUDIX domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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