6AH0K

The cryo-em structure of the precusor of human pre-catalytic spliceosome (pre-b complex)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
356
structure length
343
Chain Sequence
TWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKVNLASCAADGSVKLWSLDSVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
pubmed doi rcsb
molecule tags Splicing
molecule keywords U5snRNA
total genus 35
structure length 343
sequence length 356
ec nomenclature
pdb deposition date 2018-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00400 WD40 WD domain, G-beta repeat
K PF08799 PRP4 pre-mRNA processing factor 4 (PRP4) like
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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