6BPYA

Aspergillus fumigatus thioredoxin reductase
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
325
structure length
324
Chain Sequence
VHTKVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANTAAGGQLTTTTDIENFPGFPDGIGGAELMENMRKQSIRFGTEVITETISRVDLSSKPFKLWTEWNDGPDKEPACTADAVIIATGANARRLNLPGEETYWQNGISACAVCDGAVPIFRNKPLYVIGGGDSAAEEAMFLAKYGSSVTVLVRRDKLRASKAMAKRLLAHPKVTVRFNTVATEVLGEKKPNGLMTHLRIKNTVTGEEEIVDANGLFYAVGHDPATALVKGQIDLDEDGYIITKPGTSYTSREGVFACGDVQDKRYRQAITSAGSGCIAALEAEKFIAEAES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Thioredoxin reductase
publication title Inhibition of Aspergillus fumigatus thioredoxin reductase by ebselen: a potential antifungal drug
rcsb
source organism Neosartorya fumigata
total genus 87
structure length 324
sequence length 325
chains with identical sequence B
ec nomenclature ec 1.8.1.9: Thioredoxin-disulfide reductase.
pdb deposition date 2017-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07992 Pyr_redox_2 Pyridine nucleotide-disulphide oxidoreductase
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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