6BU9A

Drosophila dicer-2 bound to blunt dsrna
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
550
structure length
399
Chain Sequence
MEDVEIKPRGYQLRLVDHLTKSNGIVYLPTGSGKTFVAILVLKRFSQDFDKPIESGGKRALFMCNTVELARQQAMAVRRCTNFKVGFYVGWTRGMWSDEIKKNQVLVGTAQALSSLSVVIIDECHHGPRVVGLTGTNVATKLKELEITYRGNIITVSDTKEMENVMLYATKPTEVMVSFPHQEQVLTVTRLISAEIEKFYVSLIYAASIAIISLIVEFDIKRRQAETLSVKLMHRTALTLCEKIRHLLVQKLQDMTYDDDDDNVNTEEVIMCCLVFVERRYTCKCIYGLLLNYIKWQKSAIQQFRDGNANLMICSSVLEEGIDVQACNHVFILDPFNMYVQSKGRARTTEAKFVLFTKEREKTIQQIYQYRKAHNDIAEYLKDRVLEKTEPELYEIKGH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Rna binding protein/rna
molecule keywords Dicer-2, isoform A
publication title Dicer uses distinct modules for recognizing dsRNA termini.
pubmed doi rcsb
source organism Drosophila melanogaster
total genus 58
structure length 399
sequence length 550
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2017-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00035 dsrm Double-stranded RNA binding motif
A PF00270 DEAD DEAD/DEAH box helicase
A PF00271 Helicase_C Helicase conserved C-terminal domain
A PF00636 Ribonuclease_3 Ribonuclease III domain
A PF02170 PAZ PAZ domain
A PF03368 Dicer_dimer Dicer dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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