6C7YB

Crystal structure of inhibitory protein socs1 in complex with jak1 kinase domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
117
structure length
117
Chain Sequence
STHFRTFRSQADFSSITRASSLLDACGFYWGPLTVSAAHEKLKSEPEGTFLIRDSTQKNCFFAISVKTATGPTSIRINFQTGRFSLDGSKETFDCLFKLLEHYLSSPRKVLVTPLRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein, transferase/inhibitor
molecule keywords Tyrosine-protein kinase JAK1
publication title The molecular basis of JAK/STAT inhibition by SOCS1.
pubmed doi rcsb
source organism Homo sapiens
total genus 29
structure length 117
sequence length 117
ec nomenclature
pdb deposition date 2018-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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