6CEYA

Aminoglycoside phosphotransferase (2'')-ia in complex with gmppnp, magnesium, and lividomycin moieties
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
294
structure length
288
Chain Sequence
NVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/antibiotic
molecule keywords Bifunctional AAC/APH
publication title Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 102
structure length 288
sequence length 294
chains with identical sequence B, C, D
ec nomenclature ec 2.7.1.190: Aminoglycoside 2''-phosphotransferase.
pdb deposition date 2018-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01636 APH Phosphotransferase enzyme family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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