6DU6A

Crystal structure of the pyruvate kinase (pk1) from the mosquito aedes aegypti
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
507
structure length
503
Chain Sequence
SVSHLEHMCSLDIDSQTAFVRLSGIICTIGPASVAPEMLEKMMATGMNIARLNFSHGSHEYHANTIKNIREAVDNYSKKQGKPFPLAIALDTKGPEIRTGLITGEVELKKGEQIQLTTDKDHLEKGSKDKIFVDYVNIVKVVKKGDRVFVDDGLISLVVDSISGDTLTCTVENGGLLGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQGVDVIFASFIRNAAALKEIRTILGEKGKNIKIISKIENQQGMQNLDAIIAASDGIMVARGDLGIEIPAEKVFLAQKSMIARCNRAGKPVICATQMLESMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHRNLFNDLVNTTPTPLDTASSIAIAASEAAAKSRAAAVIVITTSGRSAHLISKYRPRCPIIAVTRFAQTARQCHLYRGILPVIYEQQALEDWLKDVDARVQYGMDFGKERGFLKPGNPVVVVTGWKQGSGFTNTIRIVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Aedes aegypti
publication title Distinctive regulatory properties of pyruvate kinase 1 from Aedes aegypti mosquitoes.
pubmed doi rcsb
molecule keywords Pyruvate kinase
total genus 135
structure length 503
sequence length 507
chains with identical sequence B, C, D
ec nomenclature ec 2.7.1.40: Pyruvate kinase.
pdb deposition date 2018-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00224 PK Pyruvate kinase, barrel domain
A PF02887 PK_C Pyruvate kinase, alpha/beta domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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