6EVVL

X-ray structure of the complex between human alpha thrombin and nu172, a duplex/quadruplex 26-mer dna aptamer, in the presence of potassium ions.
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
33
structure length
33
Chain Sequence
TFGSGEADCGLRPLFEKKSLEDKTERELLESYI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Prothrombin
total genus 3
structure length 33
sequence length 33
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2017-11-02
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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