6FHTA

Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in its dark adapted pr form
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
Knots found
sequence length
735
structure length
730
Chain Sequence
GAMARDPLPFFPPLYLGGPEITTENCEREPIHIPGSIQPHGALLTADGHSGEVLQMSLNAATFLGQEPTVLRGQTLAALLPEQWPALQAALPPGCPDALQYRATLDWPAAGHLSLTVHRVGELLILEFEPTEAWDSTGPHALRNAMFALESAPNLRALAEVATQTVRELTGFDRVMLYKFAPDATGEVIAEARREGLHAFLGHRFPASDIPAQARALYTRHLLRLTADTRAAAVPLDPVLNPQTNAPTPLGGAVLRATSPMHMQYLRNMGVGSSLSVSVVVGGQLWGLIACHHQTPYVLPPDLRTTLEYLGRLLSLQVQVKEAADVAAFRQSLREHHARVALAAAHSLSPHDTLSDPALDLLGLMRAGGLILRFEGRWQTLGEVPPAPAVDALLAWLETQPGALVQTDALGQLWPAPSAAGLLAISVGEGWSECLVWLRPELRLEVAWGGATPDQAKDDLGPRHSFDTYLEEKRGYAEPWHPGEIEEAQDLRDTLTGALGERLSVIRVRNTFGRYLTDQVVATLLENPEGLKMGGDRRPITILTSDLRGFTSTSEGLNPEEVVKVLNIYFGKMADVITHHGGTIDKFMGDGILVLFGAPTSQQDDALRAVACGVEMQLALREVNQQVTGLGLQPLEMGIGINTGEVVVGNIGSEKRTKYGVVGAQVNLTYRIESYTTGGQIFISSTTLEAAGDRVHVNGNRTVQPKGVKDPVVIWDVAGVGEPYNLSLAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications.
pubmed doi rcsb
molecule tags Lyase
source organism Deinococcus radiodurans
molecule keywords Bacteriophytochrome,Adenylate cyclase
total genus 218
structure length 730
sequence length 735
chains with identical sequence B
other databases KnotProt 2.0: K 41 41
ec nomenclature ec 2.7.13.3: Histidine kinase.
pdb deposition date 2018-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00211 Guanylate_cyc Adenylate and Guanylate cyclase catalytic domain
A PF00360 PHY Phytochrome region
A PF01590 GAF GAF domain
A PF08446 PAS_2 PAS fold
Image from the rcsb pdb (www.rcsb.org)
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