6JYQU

Crystal structure of upa_h99y in complex with 3-azanyl-5-(azepan-1-yl)-n-carbamimidoyl-6-(furan-2-yl)pyrazine-2-carboxamide
Total Genus 55

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
246
structure length
246
Chain Sequence
IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAYHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS11 (156-163)TI4 (59-60)TIV1 (16-19)3H2 (56-58)S5 (64-68)S1 (20-21)TI1 (27-30)TII1 (77-80)S2 (30-36)S13 (197-203)S3 (38-48)TI2 (37-37)TIV5 (99-102)S8 (99-100)TIV2 (46-49)S6 (81-90)S4 (51-54)3H3 (62-63)TI5 (72-75)S9 (104-109)TI6 (91-94)S12 (180-184)S7 (95-96)TIV11 (216-220)TIV4 (97-98)3H4 (231-233)TI7 (110-110)S14 (206-215)TII2 (125-128)TII3 (131-134)S10 (134-140)TI9 (145-148)TIV9 (192-195)TIV6 (143-146)TIV12 (219-222)TII4 (191-194)TI13 (185-186)AH1 (165-169)TIV8 (170-173)TI12 (177-180)TII'1 (172-175)S15 (226-230)TIV7 (170-172)TI11 (173-176)TII6 (222-224)AH2 (234-242)TIV3 (67-70)TIV10 (202-205)TI8 (115-118)Updating...
connected with : NaN
molecule tags Hydrolase
source organism Homo sapiens
publication title H99Y-6F-HMA-pH7
rcsb
molecule keywords Urokinase-type plasminogen activator
total genus 55
structure length 246
sequence length 246
ec nomenclature ec 3.4.21.73: U-plasminogen activator.
pdb deposition date 2019-04-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF00089 Trypsin Trypsin
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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