6MKJA

Crystal structure of penicillin binding protein 5 (pbp5) from enterococcus faecium in the closed conformation
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
sequence length
636
structure length
621
Chain Sequence
EAGEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQISNLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDTTINWQPNLVFPEMEGNDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFDLTEDAINQAISQSWVQPDYFVPLKIIDELPAGATIQEVDGRYYPLGEAAAQLIGYVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIEHEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTNGISQEDYKAYEENPEQPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLKWQKDSSWGSYQVTRVSDVSQVDLKTALIYSDNIYTAQETLKMGEKKFRTGLDKFIFGEDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFANNGTLVYPKLIADKETKDKKNVIGETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEIKGKENSFLFAFNPDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
pubmed doi rcsb
molecule tags Protein binding
source organism Enterococcus faecium
molecule keywords penicillin binding protein 5 (PBP5)
total genus 163
structure length 621
sequence length 636
ec nomenclature
pdb deposition date 2018-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00905 Transpeptidase Penicillin binding protein transpeptidase domain
A PF03717 PBP_dimer Penicillin-binding Protein dimerisation domain
A PF05223 MecA_N NTF2-like N-terminal transpeptidase domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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