6PTWD

Nmr data-driven model of kras-gmppnp:rbd-crd complex tethered to a nanodisc (state b)
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
132
structure length
132
Chain Sequence
NTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Apolipoprotein A-I
total genus 20
structure length 132
sequence length 132
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2019-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
D PF02196 RBD Raf-like Ras-binding domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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