6QU9B

Fab fragment of an antibody that inhibits polymerisation of alpha-1-antitrypsin
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
211
structure length
211
Chain Sequence
DIVMTQTPSSLSASLGGKVTITCKASQKINNYIAWYQLKPGKGPRQLIHYTSKLQPGIPSRFSGSGSGSDYSFSISNLEPEDIGTYYCLRYEDLWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterisation of explant pathological polymers from a patient with alpha-1 antitrypsin deficiency
rcsb
molecule tags Protein binding
molecule keywords FAB 4B12 heavy chain
total genus 47
structure length 211
sequence length 211
chains with identical sequence L
ec nomenclature
pdb deposition date 2019-02-26
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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