6QW64B

Structure of the human u5.u4/u6 tri-snrnp at 2.9a resolution.
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
359
structure length
359
Chain Sequence
QTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of 5' splice site transfer for human spliceosome activation.
pubmed doi rcsb
molecule tags Splicing
source organism Homo sapiens
molecule keywords U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
total genus 83
structure length 359
sequence length 359
ec nomenclature
pdb deposition date 2019-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4B PF00400 WD40 WD domain, G-beta repeat
4B PF08799 PRP4 pre-mRNA processing factor 4 (PRP4) like
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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