6QX9A1

Structure of a human fully-assembled precatalytic spliceosome (pre-b complex).
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
168
structure length
168
Chain Sequence
SAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVXXXXXXXXXXXXXXXXXXXXXXXXXXVYAPGLDIESSLKQLAERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of 5' splice site transfer for human spliceosome activation.
pubmed doi rcsb
molecule tags Splicing
source organism Homo sapiens
molecule keywords U1 snRNA
total genus 46
structure length 168
sequence length 168
ec nomenclature
pdb deposition date 2019-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A1 PF00240 ubiquitin Ubiquitin family
A1 PF01805 Surp Surp module
A1 PF12230 PRP21_like_P Pre-mRNA splicing factor PRP21 like protein
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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