6S8FF

Structure of nucleotide-bound tel1/atm
Total Genus 588
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
588
sequence length
2626
structure length
2571
Chain Sequence
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Cryo-EM structure of nucleotide-bound Tel1ATM unravels the molecular basis of inhibition and structural rationale for disease-associated mutations
rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Serine/threonine-protein kinase TEL1,Serine/threonine-protei
total genus 588
structure length 2571
sequence length 2626
chains with identical sequence H
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2019-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00454 PI3_PI4_kinase Phosphatidylinositol 3- and 4-kinase
F PF02260 FATC FATC domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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