6SV2A

Human prion protein (prp) fragment 119-231 (g127v m129 variant) complexed to icsm 18 (anti-prp therapeutic antibody) fab fragment
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
101
structure length
101
Chain Sequence
LGVYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural effects of the highly protective V127 polymorphism on human prion protein.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN
total genus 35
structure length 101
sequence length 101
ec nomenclature
pdb deposition date 2019-09-17
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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