6V4UC

Cryo-em structure of smcr8-c9orf72-wdr41 complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
419
structure length
329
Chain Sequence
TELLVLKAHHDIVRFLVQLDDYRFASAGDDGIVVVWNAQTGEKLLELNGHTQKITAIITFPNQLILTASADRTVIVWDGDTTRQVQRISCFQSTVKCLTVLQRLDVWLSGGNDLCVWNRKLDLLCKTSHLSDTGISALVEIPKNCVVAAVGKELIIFRLVAPTEGSLEWDILDHQDNILSLINVNDLSFVTGSHVGELIIWDALDWTMQALCQKNDISIHHFTCDEENVFAAVGRGLYVYSLQMKRVAHDSNVLHVARLPNRQLISCSEDGSVRIWELREGDLIGHSSSVEMFLYFEDHGLVTCSADHLIILWKNGERELRLFQKLEEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords WD repeat-containing protein 41
publication title Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD.
pubmed doi rcsb
source organism Homo sapiens
total genus 23
structure length 329
sequence length 419
ec nomenclature
pdb deposition date 2019-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00400 WD40 WD domain, G-beta repeat
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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