6VVVC

Crystal structure of a mycobacterium smegmatis transcription initiation complex with rifampicin-resistant rna polymerase
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
sequence length
1119
structure length
790
Chain Sequence
NSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLVGSDRWPVGGLEEVLAELSPIPRFDEVKASVDECKDKDMTYAAPLFDFPMMTEKGTFIINGTERVVVSQLVRSNRRLRTVGELIQNQIRVGLSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLLALGLIGSLSVYARVNPFGFIETPDYLTADEEDRHVRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVADKTGVIEEVSADYITVMADDGTRQSYRLRKFARSNHGTCANQRPIVDAGQRVEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWNIDVAAGVPDWASKLPEELYSAPADSTVATPVFDGAQEGELAGLLGSTLPNRDGEVMVDADGKSTLFDGRSGEPFPYPVTVGYMYILKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIEMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription,transferase/dna
molecule keywords RNA polymerase-binding protein RbpA
publication title The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
pubmed doi rcsb
source organism Mycolicibacterium smegmatis (strain atcc 700084 / mc(2)155)
total genus 164
structure length 790
sequence length 1119
ec nomenclature
pdb deposition date 2020-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00562 RNA_pol_Rpb2_6 RNA polymerase Rpb2, domain 6
C PF04560 RNA_pol_Rpb2_7 RNA polymerase Rpb2, domain 7
C PF04561 RNA_pol_Rpb2_2 RNA polymerase Rpb2, domain 2
C PF04563 RNA_pol_Rpb2_1 RNA polymerase beta subunit
C PF04565 RNA_pol_Rpb2_3 RNA polymerase Rpb2, domain 3
C PF10385 RNA_pol_Rpb2_45 RNA polymerase beta subunit external 1 domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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