6W1CA

Human mabs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the mxr8 receptor binding domain
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
380
structure length
380
Chain Sequence
YEHTAIIPNQVGFPYKAHVAREGYSPLTLQMQVIETSLEPTLNLEYITCDYKTKVPSPYVKCCGTAECRTQDKPEYKCAVFTGVYPFMWGGAYCFCDSENTQMSEAYVERADVCKHDHAAAYRAHTASLRAKIKVTYGTVNQTVEAYVNGDHAVTIAGTKFIFGPVSTPWTPFDTKILVYKGELYNQDFPRYGAGQPGRFGDIQSRTLDSRDLYANTGLKLARPAAGNIHVPYTQTPSGFKTWQKDRDSPLNAKAPFGCIIQTNPVRAMNCAVGNIPVSMDIADSAFTRLTDAPVISELTCTVSTCTHSSDFGGIAVLSYKVEKSGRCDIHSHSNVAVLQEVSIETEGRSVIHFSTASASPSFVVSVCSSRATCTAKCEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
pubmed doi rcsb
molecule tags Virus/immune system
source organism Mayaro virus (strain brazil)
molecule keywords E1 glycoprotein
total genus 22
structure length 380
sequence length 380
chains with identical sequence B, C, D
ec nomenclature ec 3.4.21.90: Togavirin.
pdb deposition date 2020-03-04
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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