6W9ZA

De novo designed receptor transmembrane domains enhance car-t cytotoxicity and attenuate cytokine release
Total Genus 11
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
28
structure length
28
Chain Sequence
b'PELTVALILGIFLGTFIAFWVVYLLRRL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords De novo designed receptor transmembrane domain ProMP C2.1
publication title De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
rcsb
source organism Synthetic construct
molecule tags Biosynthetic protein
total genus 11
structure length 28
sequence length 28
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2020-03-24
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...