6WJDZ

Sa-like state of human 26s proteasome with non-cleavable m1-linked hexaubiquitin and e3 ubiquitin ligase e6ap/ube3a
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
286
structure length
286
Chain Sequence
AVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
molecule keywords 26S proteasome non-ATPase regulatory subunit 1
total genus 48
structure length 286
sequence length 286
ec nomenclature
pdb deposition date 2020-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
Z PF01398 JAB JAB1/Mov34/MPN/PAD-1 ubiquitin protease
Z PF13012 MitMem_reg Maintenance of mitochondrial structure and function
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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