6XX5A

Crystal structure of the c-src sh3 domain h122r-q128k mutant in complex with ni(ii) at ph 7.5 co-crystallized with methyl beta-cyclodextrin
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
61
structure length
57
Chain Sequence
GSHMTFVALYDYESRTETDLSFKKGERLQIVGDWWLARSLTTGKTGYIPSNYVAPSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
pubmed doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords Proto-oncogene tyrosine-protein kinase Src
total genus 14
structure length 57
sequence length 61
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2020-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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