6Y7TD

Engineered conjugation of lysine-specific molecular tweezers with exos derived peptidic inhibitor enhance affinity towards target protein 14-3-3 through ditopic binding
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
10
structure length
10
Chain Sequence
QGLLDALDLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Peptide binding protein
molecule keywords 14-3-3 protein sigma
publication title Supramolecular enhancement of natural 14-3-3 protein ligands
rcsb
source organism Homo sapiens
total genus 1
structure length 10
sequence length 10
chains with identical sequence E
ec nomenclature
pdb deposition date 2020-03-02
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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