6YE3A

Il-2 in complex with a fab fragment from ufka-20
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
223
structure length
223
Chain Sequence
EVMLVESGGGLVKPGGSLKLSCAASGFSFSNYAMSWVRQTPERRLEWVALISGGGSYSYYPDSLKGRFTISRDSARNSLYLQMSSLRSEDTAMYYCARHMGYNDYLAWFAYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Chains: A,D,G
total genus 38
structure length 223
sequence length 223
chains with identical sequence D, G
ec nomenclature
pdb deposition date 2020-03-23
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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