6YVHH

Cwc22-cwc27-eif4a3 complex
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
166
structure length
162
Chain Sequence
LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWGLDVPQVSLIINYDLPNNRELYIHRIGRSGRRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords Pre-mRNA-splicing factor CWC22 homolog
total genus 51
structure length 162
sequence length 166
chains with identical sequence J, K, L
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2020-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00271 Helicase_C Helicase conserved C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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