6ZPLC

Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor, sybody sb_glyt1#7 and bound na and cl ions.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
273
structure length
273
Chain Sequence
LKIGAWVGTQPSESAIKSFQELQGRKLDIVHQFINWSTDFSWVRPYADAVYNNGSILMITWEPWEYNTVDIKNGKADAYITRMAQDMKAYGKEIWLRPLHAANGDWYPWAIGYSSRVNTNETYIAAFRHIVDIFRANGATNVKWVFNVNCDNVGNGTSYLGHYPGDNYVDYTSIDGYNWGTTQSWGSQWQSFDQVFSRAYQALASINKPIIIAEFASAEIGGNKARWITEAYNSIRTSYNKVIAAVWFHENKETDWRINSSPEALAAYREAIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the inhibition of glycine reuptake.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords Sodium- and chloride-dependent glycine transporter 1
total genus 91
structure length 273
sequence length 273
ec nomenclature ec 3.2.1.4: Cellulase.
pdb deposition date 2020-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF02156 Glyco_hydro_26 Glycosyl hydrolase family 26
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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