7A6DA

Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with rac-trans-4,4-difluorocyclopentane-1,2-diol
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
377
structure length
372
Chain Sequence
DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHLDGSRHMLSPERSIEIQHLLGSDIVMAFDESTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDSVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRACIHALIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFARNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface
doi rcsb
molecule tags Transferase
source organism Zymomonas mobilis subsp. mobilis (strain atcc 31821 / zm4 / cp4)
molecule keywords Queuine tRNA-ribosyltransferase
total genus 137
structure length 372
sequence length 377
ec nomenclature ec 2.4.2.29: tRNA-guanine(34) transglycosylase.
pdb deposition date 2020-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01702 TGT Queuine tRNA-ribosyltransferase
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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