7B5OI

Cryo-em structure of the human cak bound to icec0942 at 2.5 angstroms resolution
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
284
structure length
281
Chain Sequence
MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 2.5 angstrom -resolution structure of the human CDK-activating kinase bound to the clinical inhibitor ICEC0942.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords CDK-activating kinase assembly factor MAT1
total genus 109
structure length 281
sequence length 284
ec nomenclature
pdb deposition date 2020-12-05
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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